imipenem Gene Set
Genes
12 genes differentially expressed following the imipenem small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NFKBIB
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
|
6.07344
|
|
PEG3
|
paternally expressed 3
|
3.60782
|
|
RASSF2
|
Ras association (RalGDS/AF-6) domain family member 2
|
3.51849
|
|
CDHR2
|
cadherin-related family member 2
|
3.33458
|
|
BICDL1
|
BICD family like cargo adaptor 1
|
3.2325
|
|
TSKS
|
testis-specific serine kinase substrate
|
3.09235
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-6.95715
|
|
EPHB2
|
EPH receptor B2
|
-4.16107
|
|
CDC25B
|
cell division cycle 25B
|
-3.52106
|
|
CASK
|
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
|
-3.42153
|
|
GNMT
|
glycine N-methyltransferase
|
-3.06913
|
|
AMPD1
|
adenosine monophosphate deaminase 1
|
-3.06892
|
