| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the imipramine-1807 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ANKRD12 | ankyrin repeat domain 12 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BAX | BCL2-associated X protein |
| BBC3 | BCL2 binding component 3 |
| CABIN1 | calcineurin binding protein 1 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CELF1 | CUGBP, Elav-like family member 1 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLDN1 | claudin 1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| CYTH1 | cytohesin 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DOK4 | docking protein 4 |
| DUSP5 | dual specificity phosphatase 5 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ETV5 | ets variant 5 |
| EVI5 | ecotropic viral integration site 5 |
| FGF5 | fibroblast growth factor 5 |
| FST | follistatin |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GAS8 | growth arrest-specific 8 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC9 | histone deacetylase 9 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HHAT | hedgehog acyltransferase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HYOU1 | hypoxia up-regulated 1 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL6 | interleukin 6 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KDM6A | lysine (K)-specific demethylase 6A |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLK7 | kallikrein-related peptidase 7 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT33A | keratin 33A, type I |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| METTL3 | methyltransferase like 3 |
| MEX3D | mex-3 RNA binding family member D |
| NID1 | nidogen 1 |
| OPTN | optineurin |
| OSMR | oncostatin M receptor |
| PAPOLA | poly(A) polymerase alpha |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PHF1 | PHD finger protein 1 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIDD1 | p53-induced death domain protein 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RANBP3 | RAN binding protein 3 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SH2B1 | SH2B adaptor protein 1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| STX3 | syntaxin 3 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| TBC1D2B | TBC1 domain family, member 2B |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TM2D1 | TM2 domain containing 1 |
| TMEM194A | transmembrane protein 194A |
| TMEM47 | transmembrane protein 47 |
| TMEM50B | transmembrane protein 50B |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIM25 | tripartite motif containing 25 |
| TRIM32 | tripartite motif containing 32 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TUBA3C | tubulin, alpha 3c |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| WWOX | WW domain containing oxidoreductase |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZFX | zinc finger protein, X-linked |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF358 | zinc finger protein 358 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARL2 | ADP-ribosylation factor-like 2 |
| ARMC6 | armadillo repeat containing 6 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CDKN2AIP | CDKN2A interacting protein |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CORO1A | coronin, actin binding protein, 1A |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNASE1L1 | deoxyribonuclease I-like 1 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EXO1 | exonuclease 1 |
| FANCC | Fanconi anemia, complementation group C |
| FBXO2 | F-box protein 2 |
| FPGS | folylpolyglutamate synthase |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GMIP | GEM interacting protein |
| GPR1 | G protein-coupled receptor 1 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIST1H2BF | histone cluster 1, H2bf |
| HOXC13 | homeobox C13 |
| HOXC4 | homeobox C4 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT46 | intraflagellar transport 46 |
| IL15RA | interleukin 15 receptor, alpha |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KLHDC4 | kelch domain containing 4 |
| KRT15 | keratin 15, type I |
| KRT4 | keratin 4, type II |
| KRT8P12 | keratin 8 pseudogene 12 |
| LOC730101 | uncharacterized LOC730101 |
| MB | myoglobin |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NCS1 | neuronal calcium sensor 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NRTN | neurturin |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POLH | polymerase (DNA directed), eta |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RBL1 | retinoblastoma-like 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPS10P5 | ribosomal protein S10 pseudogene 5 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SMA4 | glucuronidase, beta pseudogene |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPATA2L | spermatogenesis associated 2-like |
| TBX19 | T-box 19 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) |
| TIMP4 | TIMP metallopeptidase inhibitor 4 |
| TKFC | triokinase/FMN cyclase |
| TMEM160 | transmembrane protein 160 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSC22D4 | TSC22 domain family, member 4 |
| ULBP2 | UL16 binding protein 2 |
| XAB2 | XPA binding protein 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF134 | zinc finger protein 134 |
| ZNF273 | zinc finger protein 273 |
| ZNF76 | zinc finger protein 76 |
| ZNF85 | zinc finger protein 85 |
| ZXDC | ZXD family zinc finger C |
