| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the imipramine-1849 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AEN | apoptosis enhancing nuclease |
| AIM2 | absent in melanoma 2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BOLA1 | bolA family member 1 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CACTIN | cactin, spliceosome C complex subunit |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CCDC71 | coiled-coil domain containing 71 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDCP1 | CUB domain containing protein 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CFAP45 | cilia and flagella associated protein 45 |
| CHKA | choline kinase alpha |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOK3 | docking protein 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXOC2 | exocyst complex component 2 |
| FLJ42627 | uncharacterized LOC645644 |
| FOXO4 | forkhead box O4 |
| FUZ | fuzzy planar cell polarity protein |
| GAMT | guanidinoacetate N-methyltransferase |
| GSN | gelsolin |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HMGXB3 | HMG box domain containing 3 |
| HRH1 | histamine receptor H1 |
| HSPA4 | heat shock 70kDa protein 4 |
| IQCK | IQ motif containing K |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| KIAA1456 | KIAA1456 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT8P12 | keratin 8 pseudogene 12 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LMNA | lamin A/C |
| MAGED2 | melanoma antigen family D2 |
| MAP7 | microtubule-associated protein 7 |
| MIIP | migration and invasion inhibitory protein |
| MLH3 | mutL homolog 3 |
| MST1 | macrophage stimulating 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NIPAL2 | NIPA-like domain containing 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PCGF2 | polycomb group ring finger 2 |
| PCM1 | pericentriolar material 1 |
| PENK | proenkephalin |
| PHACTR1 | phosphatase and actin regulator 1 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| POLL | polymerase (DNA directed), lambda |
| POM121 | POM121 transmembrane nucleoporin |
| RAB3A | RAB3A, member RAS oncogene family |
| RBM19 | RNA binding motif protein 19 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPAIN | RPA interacting protein |
| RPL35A | ribosomal protein L35a |
| RPL5 | ribosomal protein L5 |
| RRBP1 | ribosome binding protein 1 |
| RUNX1 | runt-related transcription factor 1 |
| SCAI | suppressor of cancer cell invasion |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SORT1 | sortilin 1 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| STMN1 | stathmin 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TOB2 | transducer of ERBB2, 2 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| UTRN | utrophin |
| Symbol | Name |
|---|---|
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AGBL5 | ATP/GTP binding protein-like 5 |
| AGO4 | argonaute RISC catalytic component 4 |
| AKTIP | AKT interacting protein |
| ARMC7 | armadillo repeat containing 7 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BBS10 | Bardet-Biedl syndrome 10 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CD82 | CD82 molecule |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CFAP44 | cilia and flagella associated protein 44 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CRY2 | cryptochrome circadian clock 2 |
| CSF1R | colony stimulating factor 1 receptor |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| FAM188A | family with sequence similarity 188, member A |
| FAM53B | family with sequence similarity 53, member B |
| FLCN | folliculin |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GPR63 | G protein-coupled receptor 63 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| KIAA0319L | KIAA0319-like |
| KLF11 | Kruppel-like factor 11 |
| KLHL21 | kelch-like family member 21 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYNN | myoneurin |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma |
| PIR | pirin (iron-binding nuclear protein) |
| PLA2G15 | phospholipase A2, group XV |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB33B | RAB33B, member RAS oncogene family |
| RBM41 | RNA binding motif protein 41 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RFX7 | regulatory factor X, 7 |
| RNF122 | ring finger protein 122 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SERINC5 | serine incorporator 5 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| SNX17 | sorting nexin 17 |
| SPAG4 | sperm associated antigen 4 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSBP3 | single stranded DNA binding protein 3 |
| STXBP1 | syntaxin binding protein 1 |
| SURF2 | surfeit 2 |
| TAOK1 | TAO kinase 1 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM159 | transmembrane protein 159 |
| TOM1 | target of myb1 (chicken) |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TTBK2 | tau tubulin kinase 2 |
| TUBA3C | tubulin, alpha 3c |
| TXLNG | taxilin gamma |
| URGCP | upregulator of cell proliferation |
| USB1 | U6 snRNA biogenesis 1 |
| USP19 | ubiquitin specific peptidase 19 |
| WT1-AS | WT1 antisense RNA |
| XAF1 | XIAP associated factor 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 |
| ZNF10 | zinc finger protein 10 |
| ZNF16 | zinc finger protein 16 |
| ZNF197 | zinc finger protein 197 |
| ZNF227 | zinc finger protein 227 |
| ZNF253 | zinc finger protein 253 |
| ZNF675 | zinc finger protein 675 |
| ZNF8 | zinc finger protein 8 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |