| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
193 genes differentially expressed following the imipramine-5440 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ADORA1 | adenosine A1 receptor |
| AGTR1 | angiotensin II receptor, type 1 |
| AK1 | adenylate kinase 1 |
| AKAP1 | A kinase (PRKA) anchor protein 1 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APAF1 | apoptotic peptidase activating factor 1 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CATSPERB | catsper channel auxiliary subunit beta |
| CCDC134 | coiled-coil domain containing 134 |
| CD226 | CD226 molecule |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CHD9 | chromodomain helicase DNA binding protein 9 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DLX6 | distal-less homeobox 6 |
| DNAH9 | dynein, axonemal, heavy chain 9 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPHA1 | EPH receptor A1 |
| EPHB2 | EPH receptor B2 |
| EXOC6B | exocyst complex component 6B |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 |
| FAM46C | family with sequence similarity 46, member C |
| FHL1 | four and a half LIM domains 1 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GK | glycerol kinase |
| GM2A | GM2 ganglioside activator |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HDAC6 | histone deacetylase 6 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| ICAM1 | intercellular adhesion molecule 1 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNIP1 | Kv channel interacting protein 1 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAMA4 | laminin, alpha 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP4 | microtubule-associated protein 4 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPR2 | natriuretic peptide receptor 2 |
| NRG1 | neuregulin 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OLFM1 | olfactomedin 1 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLK3 | polo-like kinase 3 |
| POPDC3 | popeye domain containing 3 |
| PTCRA | pre T-cell antigen receptor alpha |
| R3HDM1 | R3H domain containing 1 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RETN | resistin |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RUNX1 | runt-related transcription factor 1 |
| RUNX3 | runt-related transcription factor 3 |
| SECTM1 | secreted and transmembrane 1 |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLAMF8 | SLAM family member 8 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC35E2 | solute carrier family 35, member E2 |
| SNTA1 | syntrophin, alpha 1 |
| SPPL2B | signal peptide peptidase like 2B |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYNGR3 | synaptogyrin 3 |
| TCP10L | t-complex 10-like |
| TMOD2 | tropomodulin 2 (neuronal) |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TSPAN2 | tetraspanin 2 |
| ULBP1 | UL16 binding protein 1 |
| UPK3B | uroplakin 3B |
| USP46 | ubiquitin specific peptidase 46 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| WDR33 | WD repeat domain 33 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZIC3 | Zic family member 3 |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BBC3 | BCL2 binding component 3 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CD302 | CD302 molecule |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CORT | cortistatin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CTSK | cathepsin K |
| CUEDC1 | CUE domain containing 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DOCK1 | dedicator of cytokinesis 1 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DUSP2 | dual specificity phosphatase 2 |
| EDAR | ectodysplasin A receptor |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EVPL | envoplakin |
| FADS2 | fatty acid desaturase 2 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXO4 | F-box protein 4 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FRK | fyn-related Src family tyrosine kinase |
| GMPR | guanosine monophosphate reductase |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR143 | G protein-coupled receptor 143 |
| GRAMD4 | GRAM domain containing 4 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIRA | histone cell cycle regulator |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4D | histone cluster 1, H4d |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HMOX1 | heme oxygenase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL22 | interleukin 22 |
| ITGA10 | integrin, alpha 10 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0556 | KIAA0556 |
| KIAA0754 | KIAA0754 |
| KLC2 | kinesin light chain 2 |
| LHX6 | LIM homeobox 6 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MEFV | Mediterranean fever |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTA2 | metastasis associated 1 family, member 2 |
| NCALD | neurocalcin delta |
| NME5 | NME/NM23 family member 5 |
| NOL10 | nucleolar protein 10 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PDE12 | phosphodiesterase 12 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PP14571 | uncharacterized LOC100130449 |
| PRKCE | protein kinase C, epsilon |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAB30 | RAB30, member RAS oncogene family |
| RNF122 | ring finger protein 122 |
| RNF43 | ring finger protein 43 |
| RPL10L | ribosomal protein L10-like |
| SAV1 | salvador family WW domain containing protein 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRAIP | TRAF interacting protein |
| TRIM36 | tripartite motif containing 36 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| ZNF446 | zinc finger protein 446 |
| ZNF701 | zinc finger protein 701 |
| ZNF816 | zinc finger protein 816 |
