impaired hematopoiesis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical process of blood cell formation with the result of fewer of these cells being formed (Mammalian Phenotype Ontology, MP_0001606)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001606
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Genes

35 gene mutations causing the impaired hematopoiesis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAR adenosine deaminase, RNA-specific
ARNT aryl hydrocarbon receptor nuclear translocator
ASXL1 additional sex combs like transcriptional regulator 1
ATF4 activating transcription factor 4
BRCA2 breast cancer 2, early onset
BRD1 bromodomain containing 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBFB core-binding factor, beta subunit
CCR1 chemokine (C-C motif) receptor 1
CREBBP CREB binding protein
CRLF1 cytokine receptor-like factor 1
CTC1 CTS telomere maintenance complex component 1
EPOR erythropoietin receptor
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GJC1 gap junction protein, gamma 1, 45kDa
HHEX hematopoietically expressed homeobox
HLX H2.0-like homeobox
JAK2 Janus kinase 2
KDR kinase insert domain receptor
KLF1 Kruppel-like factor 1 (erythroid)
KLF2 Kruppel-like factor 2
MEIS1 Meis homeobox 1
MMP9 matrix metallopeptidase 9
PBX1 pre-B-cell leukemia homeobox 1
PDCD10 programmed cell death 10
PHC1 polyhomeotic homolog 1 (Drosophila)
RAD50 RAD50 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
TNRC6A trinucleotide repeat containing 6A
XBP1 X-box binding protein 1
XPA xeroderma pigmentosum, complementation group A
ZFPM1 zinc finger protein, FOG family member 1