impaired lung alveolus development Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description a block or reduction in the formation of the sacs for holding air in the lungs, which are formed by the terminal dilation of air passageways (Mammalian Phenotype Ontology, MP_0006027)
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37 gene mutations causing the impaired lung alveolus development phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BAG6 BCL2-associated athanogene 6
CBY1 chibby homolog 1 (Drosophila)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CREB1 cAMP responsive element binding protein 1
DHCR7 7-dehydrocholesterol reductase
EGFR epidermal growth factor receptor
ELN elastin
ERRFI1 ERBB receptor feedback inhibitor 1
FBLN1 fibulin 1
FBN1 fibrillin 1
FGF10 fibroblast growth factor 10
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FOXF1 forkhead box F1
FOXP2 forkhead box P2
HBEGF heparin-binding EGF-like growth factor
HOPX HOP homeobox
HOXA5 homeobox A5
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LMNB1 lamin B1
LYST lysosomal trafficking regulator
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
NEUROD1 neuronal differentiation 1
NPAS3 neuronal PAS domain protein 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PDGFA platelet-derived growth factor alpha polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PKDCC protein kinase domain containing, cytoplasmic
PTGES3 prostaglandin E synthase 3 (cytosolic)
RARB retinoic acid receptor, beta
TGFB3 transforming growth factor, beta 3
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM38B transmembrane protein 38B
TMTC3 transmembrane and tetratricopeptide repeat containing 3
WWTR1 WW domain containing transcription regulator 1