impaired lymphocyte transformation with phytohemagglutinin Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Normal peripheral blood lymphocytes, when stimulated by phytohemagglutinin (PHA) are cytotoxic for homologous and heterologous cells but not for autologous cells in monolayer culture. The cytotoxic effect is thought to be indicative of the immunological competence of the lymphocytes. (Human Phenotype Ontology, HP_0003347)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0003347
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Genes

3 genes associated with the impaired lymphocyte transformation with phytohemagglutinin phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
KLHDC8B kelch domain containing 8B
MYD88 myeloid differentiation primary response 88
RMRP RNA component of mitochondrial RNA processing endoribonuclease