impaired myelopoiesis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical process of bone marrow cell formation and/or the formation of bone marrow-derived blood cells with the result of fewer of these cells being formed (Mammalian Phenotype Ontology, MP_0001602)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001602
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Genes

12 gene mutations causing the impaired myelopoiesis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BTK Bruton agammaglobulinemia tyrosine kinase
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CSF3 colony stimulating factor 3 (granulocyte)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
FLT3LG fms-related tyrosine kinase 3 ligand
IL13RA1 interleukin 13 receptor, alpha 1
MMP9 matrix metallopeptidase 9
NLK nemo-like kinase
RUNX1 runt-related transcription factor 1
SOD2 superoxide dismutase 2, mitochondrial
SPI1 Spi-1 proto-oncogene