impaired social interactions Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Difficulty in social interactions related to an impairment of characteristics such as eye contact, smiling, appropriate facial expressions, and body postures and characterized by difficulty in forming peer relationships and forming friendships. (Human Phenotype Ontology, HP_0000735)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0000735
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Genes

23 genes associated with the impaired social interactions phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
ADSL adenylosuccinate lyase
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
C10ORF2 chromosome 10 open reading frame 2
CDKL5 cyclin-dependent kinase-like 5
CLP1 cleavage and polyadenylation factor I subunit 1
CNTNAP2 contactin associated protein-like 2
DEAF1 DEAF1 transcription factor
FMR1 fragile X mental retardation 1
FOXG1 forkhead box G1
GFM1 G elongation factor, mitochondrial 1
KCNT1 potassium channel, sodium activated subfamily T, member 1
KIAA2022 KIAA2022
MECP2 methyl CpG binding protein 2
MED12 mediator complex subunit 12
MEF2C myocyte enhancer factor 2C
NALCN sodium leak channel, non selective
NLGN4X neuroligin 4, X-linked
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3