impaired stratum corneum desquamation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description dysregulated shedding of the outermost layer of corneocytes, affecting the integrity and thickness of the stratum corneum; may result in xerotic and ichthyotic conditions (Mammalian Phenotype Ontology, MP_0009597)
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3 gene mutations causing the impaired stratum corneum desquamation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALOXE3 arachidonate lipoxygenase 3
CERS3 ceramide synthase 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)