inactive Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

391 genes co-occuring with the biological term inactive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACP2 acid phosphatase 2, lysosomal
ACPP acid phosphatase, prostate
ADAR adenosine deaminase, RNA-specific
ADARB1 adenosine deaminase, RNA-specific, B1
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADORA2A adenosine A2a receptor
ADRB2 adrenoceptor beta 2, surface
AGXT alanine-glyoxylate aminotransferase
AIRE autoimmune regulator
AKAP13 A kinase (PRKA) anchor protein 13
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPL alkaline phosphatase, liver/bone/kidney
AMH anti-Mullerian hormone
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AOX1 aldehyde oxidase 1
APAF1 apoptotic peptidase activating factor 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARF4 ADP-ribosylation factor 4
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARRB1 arrestin, beta 1
AS3MT arsenite methyltransferase
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ATM ATM serine/threonine kinase
AVPR1A arginine vasopressin receptor 1A
BAIAP2 BAI1-associated protein 2
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BDNF brain-derived neurotrophic factor
BRCA1 breast cancer 1, early onset
BST2 bone marrow stromal cell antigen 2
CABIN1 calcineurin binding protein 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMP cathelicidin antimicrobial peptide
CANT1 calcium activated nucleotidase 1
CAPN2 calpain 2, (m/II) large subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCNB1 cyclin B1
CCNT1 cyclin T1
CCR2 chemokine (C-C motif) receptor 2
CCS copper chaperone for superoxide dismutase
CD28 CD28 molecule
CD40LG CD40 ligand
CDC25C cell division cycle 25C
CDC34 cell division cycle 34
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDK4 cyclin-dependent kinase 4
CDK7 cyclin-dependent kinase 7
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFB complement factor B
CFD complement factor D (adipsin)
CFI complement factor I
CFL1 cofilin 1 (non-muscle)
CHD6 chromodomain helicase DNA binding protein 6
CHRM2 cholinergic receptor, muscarinic 2
CHUK conserved helix-loop-helix ubiquitous kinase
CNR1 cannabinoid receptor 1 (brain)
CRB2 crumbs family member 2
CRYAA crystallin, alpha A
CRYBA1 crystallin, beta A1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSF1R colony stimulating factor 1 receptor
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTCF CCCTC-binding factor (zinc finger protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSH cathepsin H
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DGKD diacylglycerol kinase, delta 130kDa
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DNASE1L3 deoxyribonuclease I-like 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
DPF3 D4, zinc and double PHD fingers, family 3
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
DUSP26 dual specificity phosphatase 26 (putative)
DUSP5 dual specificity phosphatase 5
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF3F eukaryotic translation initiation factor 3, subunit F
EPHB2 EPH receptor B2
EPHB3 EPH receptor B3
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
F2 coagulation factor II (thrombin)
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL2 coagulation factor II (thrombin) receptor-like 2
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FANCM Fanconi anemia, complementation group M
FAS Fas cell surface death receptor
FES FES proto-oncogene, tyrosine kinase
FGF9 fibroblast growth factor 9
FLT1 fms-related tyrosine kinase 1
FNBP1L formin binding protein 1-like
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXF1 forkhead box F1
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FSHR follicle stimulating hormone receptor
FTO fat mass and obesity associated
G6PD glucose-6-phosphate dehydrogenase
GAK cyclin G associated kinase
GALK1 galactokinase 1
GAST gastrin
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GDF2 growth differentiation factor 2
GDF5 growth differentiation factor 5
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GIP gastric inhibitory polypeptide
GLTP glycolipid transfer protein
GLTPP1 glycolipid transfer protein pseudogene 1
GNAS GNAS complex locus
GRK4 G protein-coupled receptor kinase 4
GRM1 glutamate receptor, metabotropic 1
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GTF2B general transcription factor IIB
H2AFX H2A histone family, member X
H2AFY H2A histone family, member Y
HCAR2 hydroxycarboxylic acid receptor 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H1C histone cluster 1, H1c
HLA-DRA major histocompatibility complex, class II, DR alpha
HMBS hydroxymethylbilane synthase
HMOX2 heme oxygenase 2
HNF1A HNF1 homeobox A
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HPRT1 hypoxanthine phosphoribosyltransferase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HRH3 histamine receptor H3
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
HSPA8 heat shock 70kDa protein 8
HTRA1 HtrA serine peptidase 1
HTRA2 HtrA serine peptidase 2
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL2 interleukin 2
IL23A interleukin 23, alpha subunit p19
IL33R interleukin 33 receptor
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
INS insulin
IRAK1 interleukin-1 receptor-associated kinase 1
ISG15 ISG15 ubiquitin-like modifier
ITCH itchy E3 ubiquitin protein ligase
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB7 integrin, beta 7
JAK1 Janus kinase 1
JAK3 Janus kinase 3
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KDM1A lysine (K)-specific demethylase 1A
KDR kinase insert domain receptor
KEL Kell blood group, metallo-endopeptidase
KIF17 kinesin family member 17
KIF2C kinesin family member 2C
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF6 Kruppel-like factor 6
KRT18 keratin 18, type I
LACRT lacritin
LCK LCK proto-oncogene, Src family tyrosine kinase
LEPR leptin receptor
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGMN legumain
LHCGR luteinizing hormone/choriogonadotropin receptor
LIPC lipase, hepatic
LIPE lipase, hormone-sensitive
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRRK1 leucine-rich repeat kinase 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC4R melanocortin 4 receptor
MGP matrix Gla protein
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPL MPL proto-oncogene, thrombopoietin receptor
MTERF1 mitochondrial transcription termination factor 1
MTM1 myotubularin 1
MTMR3 myotubularin related protein 3
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
NAMPT nicotinamide phosphoribosyltransferase
NCF1C neutrophil cytosolic factor 1C pseudogene
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPY1R neuropeptide Y receptor Y1
NUPR1 nuclear protein, transcriptional regulator, 1
OXSR1 oxidative stress responsive 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAEP progestagen-associated endometrial protein
PANK2 pantothenate kinase 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE4A phosphodiesterase 4A, cAMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PEAK1 pseudopodium-enriched atypical kinase 1
PGR progesterone receptor
PHF8 PHD finger protein 8
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAU plasminogen activator, urokinase
PLD2 phospholipase D2
PLTP phospholipid transfer protein
PML promyelocytic leukemia
POU2F1 POU class 2 homeobox 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPME1 protein phosphatase methylesterase 1
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRMT1 protein arginine methyltransferase 1
PRTN3 proteinase 3
PTEN phosphatase and tensin homolog
PTGES2 prostaglandin E synthase 2
PTH parathyroid hormone
PTMA prothymosin, alpha
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRS protein tyrosine phosphatase, receptor type, S
RAB13 RAB13, member RAS oncogene family
RAB28 RAB28, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RETN resistin
RHO rhodopsin
RHOH ras homolog family member H
RNASEH1 ribonuclease H1
RNF146 ring finger protein 146
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RUNX3 runt-related transcription factor 3
RUVBL2 RuvB-like AAA ATPase 2
RYK receptor-like tyrosine kinase
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAG S-antigen; retina and pineal gland (arrestin)
SCP2 sterol carrier protein 2
SCPEP1 serine carboxypeptidase 1
SELE selectin E
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SHARPIN SHANK-associated RH domain interactor
SIRT6 sirtuin 6
SKI SKI proto-oncogene
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SMN2 survival of motor neuron 2, centromeric
SOCS1 suppressor of cytokine signaling 1
SOD1 superoxide dismutase 1, soluble
SPAST spastin
SPINT1 serine peptidase inhibitor, Kunitz type 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
STS steroid sulfatase (microsomal), isozyme S
TASP1 taspase, threonine aspartase, 1
TCF23 transcription factor 23
TERT telomerase reverse transcriptase
TEX14 testis expressed 14
TFPI2 tissue factor pathway inhibitor 2
TGS1 trimethylguanosine synthase 1
TJP1 tight junction protein 1
TMPRSS4 transmembrane protease, serine 4
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNNT2 troponin T type 2 (cardiac)
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TPI1 triosephosphate isomerase 1
TPSAB1 tryptase alpha/beta 1
TRIB1 tribbles pseudokinase 1
TSHR thyroid stimulating hormone receptor
TYMS thymidylate synthetase
UBXN2A UBX domain protein 2A
UGDH UDP-glucose 6-dehydrogenase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
ULK4 unc-51 like kinase 4
USP21 ubiquitin specific peptidase 21
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VCL vinculin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIPR2 vasoactive intestinal peptide receptor 2
VWF von Willebrand factor
WEE1 WEE1 G2 checkpoint kinase
WNT5A wingless-type MMTV integration site family, member 5A
WRN Werner syndrome, RecQ helicase-like
WWP1 WW domain containing E3 ubiquitin protein ligase 1
YBX3 Y box binding protein 3
ZBTB16 zinc finger and BTB domain containing 16
ZNF148 zinc finger protein 148