increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Gene Set

Dataset IMPC Knockout Mouse Phenotypes
Category disease or phenotype associations
Type phenotype
Description a greater number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release (Mammalian Phenotype Ontology, MP_0010168)
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Genes

10 gene knockouts causing the increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number phenotype in mic from the IMPC Knockout Mouse Phenotypes dataset.

Symbol Name
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
COG6 component of oligomeric golgi complex 6
DPH6 diphthamine biosynthesis 6
DUOXA2 dual oxidase maturation factor 2
FAM83H family with sequence similarity 83, member H
HBS1L HBS1-like translational GTPase
LTN1 listerin E3 ubiquitin protein ligase 1
MMP20 matrix metallopeptidase 20
SIK3 SIK family kinase 3
SPRED1 sprouty-related, EVH1 domain containing 1