increased aggression Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description when compared to controls, subjects exhibit greater than the normal level of domineering, assault posture and/or hostile physical action (Mammalian Phenotype Ontology, MP_0005655)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005655
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Genes

37 gene mutations causing the increased aggression phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADORA2A adenosine A2a receptor
BDNF brain-derived neurotrophic factor
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLU clusterin
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FEV FEV (ETS oncogene family)
FMR1 fragile X mental retardation 1
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GIF gastric intrinsic factor (vitamin B synthesis)
GRN granulin
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTT huntingtin
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IL6 interleukin 6
LRRC7 leucine rich repeat containing 7
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing
MAOA monoamine oxidase A
NOS1 nitric oxide synthase 1 (neuronal)
NPY1R neuropeptide Y receptor Y1
NPY4R neuropeptide Y receptor Y4
NR2E1 nuclear receptor subfamily 2, group E, member 1
NT5E 5'-nucleotidase, ecto (CD73)
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
POMC proopiomelanocortin
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
SHANK3 SH3 and multiple ankyrin repeat domains 3
SYN1 synapsin I
SYN2 synapsin II
TPH2 tryptophan hydroxylase 2
ZEB1 zinc finger E-box binding homeobox 1