increased cardiomyocyte apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the number of cardiac muscle cells undergoing programmed cell death (Mammalian Phenotype Ontology, MP_0003222)
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32 gene mutations causing the increased cardiomyocyte apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADM adrenomedullin
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
BAG3 BCL2-associated athanogene 3
CALCRL calcitonin receptor-like
CALR calreticulin
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CHD7 chromodomain helicase DNA binding protein 7
CXADR coxsackie virus and adenovirus receptor
FGF2 fibroblast growth factor 2 (basic)
HDAC2 histone deacetylase 2
HMOX1 heme oxygenase 1
INPP5F inositol polyphosphate-5-phosphatase F
IVNS1ABP influenza virus NS1A binding protein
KIFAP3 kinesin-associated protein 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
RASA1 RAS p21 protein activator (GTPase activating protein) 1
SIRT7 sirtuin 7
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SOD2 superoxide dismutase 2, mitochondrial
SOS1 son of sevenless homolog 1 (Drosophila)
STAT1 signal transducer and activator of transcription 1, 91kDa
TCAP titin-cap
TERC telomerase RNA component
TRIM54 tripartite motif containing 54
UBE4B ubiquitination factor E4B
XIRP2 xin actin binding repeat containing 2
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta