increased circulating estrogen level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than normal blood concentration of any substance that causes development of the female reproductive organs and secondary sexual characteristics (Mammalian Phenotype Ontology, MP_0003370)
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15 gene mutations causing the increased circulating estrogen level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BGLAP bone gamma-carboxyglutamate (gla) protein
CHST10 carbohydrate sulfotransferase 10
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
ESR1 estrogen receptor 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GPRC6A G protein-coupled receptor, class C, group 6, member A
INHA inhibin, alpha
LHCGR luteinizing hormone/choriogonadotropin receptor
NCOA1 nuclear receptor coactivator 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1H3 nuclear receptor subfamily 1, group H, member 3
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TIMP1 TIMP metallopeptidase inhibitor 1