increased circulating testosterone level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the normal blood concentration of a potent androgen that promotes development of male secondary sex characteristics and the development of spermatozoa and may regulate sexual desire and help maintain bone and muscle health in both males and females (Mammalian Phenotype Ontology, MP_0002781)
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18 gene mutations causing the increased circulating testosterone level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AR androgen receptor
AVPR1B arginine vasopressin receptor 1B
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
ESR1 estrogen receptor 1
FKBP4 FK506 binding protein 4, 59kDa
FSHR follicle stimulating hormone receptor
HMGN3 high mobility group nucleosomal binding domain 3
LHCGR luteinizing hormone/choriogonadotropin receptor
LRP2 low density lipoprotein receptor-related protein 2
NPR1 natriuretic peptide receptor 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
POR P450 (cytochrome) oxidoreductase
PYY peptide YY
TIMP1 TIMP metallopeptidase inhibitor 1
ZBTB16 zinc finger and BTB domain containing 16