increased dendritic cell number Gene Set

Dataset	MPO Gene-Phenotype Associations
Category	disease or phenotype associations
Type	phenotype
Description	greater number of a cells of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation (Mammalian Phenotype Ontology, MP_0008126)
External Link	http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008126
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Genes

20 gene mutations causing the increased dendritic cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol	Name
ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
ADA	adenosine deaminase
AIRE	autoimmune regulator
CX3CR1	chemokine (C-X3-C motif) receptor 1
FOXP3	forkhead box P3
IL10	interleukin 10
IL18	interleukin 18
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LAIR1	leukocyte-associated immunoglobulin-like receptor 1
MAVS	mitochondrial antiviral signaling protein
MYD88	myeloid differentiation primary response 88
PLA2G2D	phospholipase A2, group IID
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RUNX3	runt-related transcription factor 3
TNF	tumor necrosis factor
TRAF3IP2	TRAF3 interacting protein 2
TYROBP	TYRO protein tyrosine kinase binding protein
XCL1	chemokine (C motif) ligand 1
ZBTB46	zinc finger and BTB domain containing 46