increased fat cell size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased size of fat-storing cells found mostly in the abdominal cavity and subcutaneous tissue of mammals (Mammalian Phenotype Ontology, MP_0006094)
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45 gene mutations causing the increased fat cell size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALMS1 Alstrom syndrome protein 1
ANKRD26 ankyrin repeat domain 26
AQP7 aquaporin 7
BBS12 Bardet-Biedl syndrome 12
BRD2 bromodomain containing 2
CES1 carboxylesterase 1
CIDEB cell death-inducing DFFA-like effector b
CLOCK clock circadian regulator
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTF1 cardiotrophin 1
CXCL14 chemokine (C-X-C motif) ligand 14
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
ESR1 estrogen receptor 1
FEN1 flap structure-specific endonuclease 1
FFAR4 free fatty acid receptor 4
FGF21 fibroblast growth factor 21
FGL1 fibrinogen-like 1
HDC histidine decarboxylase
HRH1 histamine receptor H1
KDM3A lysine (K)-specific demethylase 3A
KSR1 kinase suppressor of ras 1
LEP leptin
LIPE lipase, hormone-sensitive
MC3R melanocortin 3 receptor
MMP19 matrix metallopeptidase 19
MRAP2 melanocortin 2 receptor accessory protein 2
NCOA3 nuclear receptor coactivator 3
NMU neuromedin U
NOS3 nitric oxide synthase 3 (endothelial cell)
OMA1 OMA1 zinc metallopeptidase
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLSCR1 phospholipid scramblase 1
PLSCR3 phospholipid scramblase 3
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PRLH prolactin releasing hormone
PROX1 prospero homeobox 1
RSC1A1 regulatory solute carrier protein, family 1, member 1
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SORBS1 sorbin and SH3 domain containing 1
TBC1D4 TBC1 domain family, member 4
WDTC1 WD and tetratricopeptide repeats 1