increased interleukin-1 alpha secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the production or release of an interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form; both membrane-bound and secreted forms of interleukin-1alpha are biologically active (Mammalian Phenotype Ontology, MP_0008654)
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5 gene mutations causing the increased interleukin-1 alpha secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BPIFA1 BPI fold containing family A, member 1
CD300LF CD300 molecule-like family member f
CLEC6A C-type lectin domain family 6, member A
MEFV Mediterranean fever
MMP1 matrix metallopeptidase 1