increased long bone epiphyseal plate size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the normal size of the cartilaginous center of ossification located at one or both ends of bones between the epiphysis (end) and the diaphysis (shaft) of long bones; longitudinal growth of the bone occurs at the plate during development in children and juveniles (Mammalian Phenotype Ontology, MP_0006398)
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23 gene mutations causing the increased long bone epiphyseal plate size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ARSB arylsulfatase B
CAV1 caveolin 1, caveolae protein, 22kDa
CHAD chondroadherin
COL2A1 collagen, type II, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CTGF connective tissue growth factor
CTSK cathepsin K
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
FGF18 fibroblast growth factor 18
FGF21 fibroblast growth factor 21
FGFR3 fibroblast growth factor receptor 3
MMP13 matrix metallopeptidase 13
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
PHEX phosphate regulating endopeptidase homolog, X-linked
SIK3 SIK family kinase 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
THRA thyroid hormone receptor, alpha
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor