increased mortality induced by gamma-irradiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater sensitivity to doses of ionizing radiation (Mammalian Phenotype Ontology, MP_0001658)
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29 gene mutations causing the increased mortality induced by gamma-irradiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATM ATM serine/threonine kinase
BRCA1 breast cancer 1, early onset
CCNG1 cyclin G1
COPS6 COP9 signalosome subunit 6
EWSR1 EWS RNA-binding protein 1
FUS FUS RNA binding protein
GPX4 glutathione peroxidase 4
H2AFX H2A histone family, member X
HMGN1 high mobility group nucleosome binding domain 1
ING1 inhibitor of growth family, member 1
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KMT2E lysine (K)-specific methyltransferase 2E
MCPH1 microcephalin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MUS81 MUS81 structure-specific endonuclease subunit
NBN nibrin
PARG poly (ADP-ribose) glycohydrolase
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PER2 period circadian clock 2
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RPL27A ribosomal protein L27a
SNAI2 snail family zinc finger 2
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
UIMC1 ubiquitin interaction motif containing 1
USP1 ubiquitin specific peptidase 1