increased mortality induced by ionizing radiation Gene Set

Dataset MGI Mouse Phenotype Associations 2023
Category disease or phenotype associations
Type phenotype
Description greater sensitivity to doses of ionizing radiation that include ultraviolet light, X-rays, or gamma rays, resulting in death (Mammalian Phenotype Ontology, MP_0003992)
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Genes

18 gene mutations causing the increased mortality induced by ionizing radiation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

Symbol Name
BID BH3 interacting domain death agonist
BRCA2 breast cancer 2, early onset
ERC1 ELKS/RAB6-interacting/CAST family member 1
JAM2 junctional adhesion molecule 2
KITLG KIT ligand
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
NOS2 nitric oxide synthase 2, inducible
PARP1 poly (ADP-ribose) polymerase 1
PRAP1 proline-rich acidic protein 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTCH1 patched 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
SCAI suppressor of cancer cell invasion
SPINDOC spindlin interactor and repressor of chromatin binding
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1