increased number of howell-jolly bodies Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormal presence of basophilic nuclear remnants of condensed DNA (1 to 2 um in diameter) in circulating erythrocytes, typically seen in severe hemolytic anemias or after splenectomy; these inclusions are normally removed by the spleen but will persist in individuals with functional hyposplenia or asplenia (Mammalian Phenotype Ontology, MP_0010178)
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11 gene mutations causing the increased number of howell-jolly bodies phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ASXL1 additional sex combs like transcriptional regulator 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
E2F4 E2F transcription factor 4, p107/p130-binding
GATA1 GATA binding protein 1 (globin transcription factor 1)
MYB v-myb avian myeloblastosis viral oncogene homolog
NFE2L2 nuclear factor, erythroid 2-like 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SAMD9L sterile alpha motif domain containing 9-like
SIN3B SIN3 transcription regulator family member B
SMAP1 small ArfGAP 1
TLX1 T-cell leukemia homeobox 1