increased plasma cell number Gene Set

Dataset	MPO Gene-Phenotype Associations
Category	disease or phenotype associations
Type	phenotype
Description	greater number of terminally differentiated, post-mitotic, short-lived cells of the B cell lineage devoted to producing large amounts of immunoglobulin (Mammalian Phenotype Ontology, MP_0008097)
External Link	http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008097
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Genes

25 gene mutations causing the increased plasma cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol	Name
CEBPE	CCAAT/enhancer binding protein (C/EBP), epsilon
ESR1	estrogen receptor 1
ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAS	Fas cell surface death receptor
FASLG	Fas ligand (TNF superfamily, member 6)
FBN1	fibrillin 1
ICOS	inducible T-cell co-stimulator
IGHM	immunoglobulin heavy constant mu
IL10	interleukin 10
IL2	interleukin 2
IL2RB	interleukin 2 receptor, beta
JAK1	Janus kinase 1
LAT	linker for activation of T cells
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LYN	LYN proto-oncogene, Src family tyrosine kinase
MADCAM1	mucosal vascular addressin cell adhesion molecule 1
PRKDC	protein kinase, DNA-activated, catalytic polypeptide
PTPN6	protein tyrosine phosphatase, non-receptor type 6
PTPRC	protein tyrosine phosphatase, receptor type, C
RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF5	Ras association (RalGDS/AF-6) domain family member 5
TANK	TRAF family member-associated NFKB activator
TNIP1	TNFAIP3 interacting protein 1
WAS	Wiskott-Aldrich syndrome
ZC3H12A	zinc finger CCCH-type containing 12A