increased prostaglandin level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the amount in the body of any of a class of mediators with effects of vasodilation, vasoconstriction, and smooth muscle stimulation (Mammalian Phenotype Ontology, MP_0009814)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009814
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Genes

13 gene mutations causing the increased prostaglandin level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APC adenomatous polyposis coli
APOE apolipoprotein E
DUSP1 dual specificity phosphatase 1
FADS1 fatty acid desaturase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
MMP9 matrix metallopeptidase 9
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
XPA xeroderma pigmentosum, complementation group A
Funding