increased regulatory t cell number Gene Set

Dataset	MPO Gene-Phenotype Associations
Category	disease or phenotype associations
Type	phenotype
Description	greater number of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity (Mammalian Phenotype Ontology, MP_0004973)
External Link	http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0004973
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Genes

17 gene mutations causing the increased regulatory t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol	Name
BCL2L11	BCL2-like 11 (apoptosis facilitator)
CD247	CD247 molecule
CD5	CD5 molecule
CTSV	cathepsin V
FOXP3	forkhead box P3
IL2	interleukin 2
KRAS	Kirsten rat sarcoma viral oncogene homolog
LAIR1	leukocyte-associated immunoglobulin-like receptor 1
PDCD1	programmed cell death 1
PEX3	peroxisomal biogenesis factor 3
PI16	peptidase inhibitor 16
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SETD5	SET domain containing 5
SYTL1	synaptotagmin-like 1
TGFB1	transforming growth factor, beta 1
TXNIP	thioredoxin interacting protein
WDR37	WD repeat domain 37