increased retinal ganglion cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater number of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain (Mammalian Phenotype Ontology, MP_0002983)
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7 gene mutations causing the increased retinal ganglion cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
DSCAM Down syndrome cell adhesion molecule
GDF11 growth differentiation factor 11
NEUROD1 neuronal differentiation 1
PANX1 pannexin 1
PDCD1 programmed cell death 1
PTF1A pancreas specific transcription factor, 1a
RORB RAR-related orphan receptor B