increased secondary ovarian follicle number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than normal numbers of the ovarian follicle in which the primary oocyte attains its full size and is surrounded by an extracellular glycoprotein layer (zona pellucida) that separates it from a peripheral layer of follicular cells permeated by one or more fluid-filled antra; the primary oocyte occupies the cumulus oophorus while the theca of the follicle develops into internal and external layers (Mammalian Phenotype Ontology, MP_0011128)
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3 gene mutations causing the increased secondary ovarian follicle number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
GNRHR gonadotropin-releasing hormone receptor
PABPC1L poly(A) binding protein, cytoplasmic 1-like
TIPARP TCDD-inducible poly(ADP-ribose) polymerase