increased sensitivity to skin irradiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased incidence of aberrant or damaged cells due to irradiation induced genotoxic damage (Mammalian Phenotype Ontology, MP_0001203)
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8 gene mutations causing the increased sensitivity to skin irradiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CASP14 caspase 14, apoptosis-related cysteine peptidase
DDB2 damage-specific DNA binding protein 2, 48kDa
E2F1 E2F transcription factor 1
ERCC8 excision repair cross-complementation group 8
GADD45A growth arrest and DNA-damage-inducible, alpha
HMGN1 high mobility group nucleosome binding domain 1
POLH polymerase (DNA directed), eta
XPC xeroderma pigmentosum, complementation group C