increased susceptibility to age-related hearing loss Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than normal loss of hearing associated with advancing age, manifest as reduced ability to perceive or discriminate sounds; the pattern and age of onset vary (Mammalian Phenotype Ontology, MP_0004748)
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19 gene mutations causing the increased susceptibility to age-related hearing loss phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACTG1 actin gamma 1
ADGRV1 adhesion G protein-coupled receptor V1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BARHL1 BarH-like homeobox 1
CDH23 cadherin-related 23
COL1A1 collagen, type I, alpha 1
CS citrate synthase
FBXO2 F-box protein 2
FIGN fidgetin
FSCN2 fascin actin-bundling protein 2, retinal
LRP2 low density lipoprotein receptor-related protein 2
MYH9 myosin, heavy chain 9, non-muscle
MYO7A myosin VIIA
NDP Norrie disease (pseudoglioma)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGFR nerve growth factor receptor
POLG polymerase (DNA directed), gamma
SOD1 superoxide dismutase 1, soluble
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b