increased susceptibility to diet-induced obesity Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description more likely to become excessively overweight or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat (Mammalian Phenotype Ontology, MP_0005658)
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42 gene mutations causing the increased susceptibility to diet-induced obesity phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA1B adrenoceptor alpha 1B
APOC3 apolipoprotein C-III
BBS12 Bardet-Biedl syndrome 12
BCO1 beta-carotene oxygenase 1
CARTPT CART prepropeptide
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL13 chemokine (C-C motif) ligand 13
CLOCK clock circadian regulator
CTF1 cardiotrophin 1
DDIT3 DNA-damage-inducible transcript 3
FABP2 fatty acid binding protein 2, intestinal
FFAR4 free fatty acid receptor 4
FOXO1 forkhead box O1
FTO fat mass and obesity associated
GPR26 G protein-coupled receptor 26
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
KDM3A lysine (K)-specific demethylase 3A
LEPR leptin receptor
LTA lymphotoxin alpha
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MMP19 matrix metallopeptidase 19
NCOR2 nuclear receptor corepressor 2
NMUR2 neuromedin U receptor 2
NPBWR1 neuropeptides B/W receptor 1
NPY5R neuropeptide Y receptor Y5
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OMA1 OMA1 zinc metallopeptidase
OSMR oncostatin M receptor
PCSK1 proprotein convertase subtilisin/kexin type 1
POMC proopiomelanocortin
PPARA peroxisome proliferator-activated receptor alpha
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRLH prolactin releasing hormone
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
SIM1 single-minded family bHLH transcription factor 1
SIRT3 sirtuin 3
SLC30A8 solute carrier family 30 (zinc transporter), member 8
TLR5 toll-like receptor 5
TNF tumor necrosis factor