increased susceptibility to induced arthritis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description more likely to be stricken with changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures that are induced by inflammatory responses caused by chemical or mechanical agents (Mammalian Phenotype Ontology, MP_0003724)
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26 gene mutations causing the increased susceptibility to induced arthritis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
C1QTNF3 C1q and tumor necrosis factor related protein 3
CD200 CD200 molecule
CD274 CD274 molecule
CD44 CD44 molecule (Indian blood group)
CYTL1 cytokine-like 1
DUSP1 dual specificity phosphatase 1
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FFAR2 free fatty acid receptor 2
FPR2 formyl peptide receptor 2
IFNGR1 interferon gamma receptor 1
IGHM immunoglobulin heavy constant mu
IL1R1 interleukin 1 receptor, type I
IL27RA interleukin 27 receptor, alpha
IL6ST interleukin 6 signal transducer
LGALS9B lectin, galactoside-binding, soluble, 9B
MIR140 microRNA 140
PECAM1 platelet/endothelial cell adhesion molecule 1
PGLYRP1 peptidoglycan recognition protein 1
PPARG peroxisome proliferator-activated receptor gamma
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SOCS3 suppressor of cytokine signaling 3
SOD3 superoxide dismutase 3, extracellular
TLR4 toll-like receptor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa