increased susceptibility to noise-induced hearing loss Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than normal reduction in hearing sensitivity following exposure to acute noise that is injurious to the cochlea (Mammalian Phenotype Ontology, MP_0004597)
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12 gene mutations causing the increased susceptibility to noise-induced hearing loss phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
CDH23 cadherin-related 23
DMD dystrophin
GJC3 gap junction protein, gamma 3, 30.2kDa
GPX1 glutathione peroxidase 1
GRID1 glutamate receptor, ionotropic, delta 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
OPRL1 opiate receptor-like 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SOD1 superoxide dismutase 1, soluble
TRPV4 transient receptor potential cation channel, subfamily V, member 4