increased susceptibility to otitis media Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater likelihood of middle ear inflammation, with an accumulation of a thick, mucous-like fluid; usually associated with a viral or bacterial respiratory infection (Mammalian Phenotype Ontology, MP_0001850)
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25 gene mutations causing the increased susceptibility to otitis media phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CBY1 chibby homolog 1 (Drosophila)
CHD7 chromodomain helicase DNA binding protein 7
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DNAH5 dynein, axonemal, heavy chain 5
DPCD deleted in primary ciliary dyskinesia homolog (mouse)
E2F4 E2F transcription factor 4, p107/p130-binding
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXO11 F-box protein 11
FGFR1 fibroblast growth factor receptor 1
IDUA iduronidase, alpha-L-
ISL1 ISL LIM homeobox 1
KIF27 kinesin family member 27
MECOM MDS1 and EVI1 complex locus
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAGLU N-acetylglucosaminidase, alpha
PHEX phosphate regulating endopeptidase homolog, X-linked
RPL38 ribosomal protein L38
SALL4 spalt-like transcription factor 4
SH3PXD2B SH3 and PX domains 2B
STK36 serine/threonine kinase 36
TBX1 T-box 1
TGIF1 TGFB-induced factor homeobox 1
TP73 tumor protein p73
TTLL1 tubulin tyrosine ligase-like family member 1
ULK4 unc-51 like kinase 4