increased susceptibility to viral infection induced morbidity/mortality Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased likelihood that an organism will display the expected moribund state caused by a viral invasion or from components of or toxins produced by a virus (Mammalian Phenotype Ontology, MP_0009791)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009791
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Genes

30 gene mutations causing the increased susceptibility to viral infection induced morbidity/mortality phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CCR2 chemokine (C-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
FLT3 fms-related tyrosine kinase 3
FOXN1 forkhead box N1
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM3 interferon induced transmembrane protein 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL15 interleukin 15
IL34 interleukin 34
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
MAVS mitochondrial antiviral signaling protein
MB21D1 Mab-21 domain containing 1
MMP9 matrix metallopeptidase 9
MSR1 macrophage scavenger receptor 1
MX1 MX dynamin-like GTPase 1
NCR1 natural cytotoxicity triggering receptor 1
PRF1 perforin 1 (pore forming protein)
SARM1 sterile alpha and TIR motif containing 1
SELK selenoprotein K
SFN stratifin
STAT2 signal transducer and activator of transcription 2, 113kDa
TICAM1 toll-like receptor adaptor molecule 1
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TMEM173 transmembrane protein 173
TYK2 tyrosine kinase 2