increased susceptibility to weight loss Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater decrease in body weight over time when compared to the average decrease in weight in response to dietary modification, fasting or caloric restriction, infection or xenobiotic treatment (Mammalian Phenotype Ontology, MP_0010180)
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32 gene mutations causing the increased susceptibility to weight loss phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACSS1 acyl-CoA synthetase short-chain family member 1
ADAM17 ADAM metallopeptidase domain 17
AGRP agouti related neuropeptide
AMACR alpha-methylacyl-CoA racemase
AQP3 aquaporin 3 (Gill blood group)
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
CTH cystathionine gamma-lyase
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DLL1 delta-like 1 (Drosophila)
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
FADS2 fatty acid desaturase 2
GPR15 G protein-coupled receptor 15
HMGN3 high mobility group nucleosomal binding domain 3
HSPA4L heat shock 70kDa protein 4-like
IL17RE interleukin 17 receptor E
LIF leukemia inhibitory factor
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MUC2 mucin 2, oligomeric mucus/gel-forming
NLRP6 NLR family, pyrin domain containing 6
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
PEX7 peroxisomal biogenesis factor 7
PMCH pro-melanin-concentrating hormone
PNRC2 proline-rich nuclear receptor coactivator 2
SCP2 sterol carrier protein 2
SEPP1 selenoprotein P, plasma, 1
SGK1 serum/glucocorticoid regulated kinase 1
TDP2 tyrosyl-DNA phosphodiesterase 2
TKTL1 transketolase-like 1
YIPF6 Yip1 domain family, member 6