increased thymocyte number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than expected number of immature T cells located in the thymus (Mammalian Phenotype Ontology, MP_0000714)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000714
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Genes

25 gene mutations causing the increased thymocyte number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BAX BCL2-associated X protein
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD7 CD7 molecule
CDK6 cyclin-dependent kinase 6
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CORO1A coronin, actin binding protein, 1A
E2F1 E2F transcription factor 1
FOXN1 forkhead box N1
GADD45A growth arrest and DNA-damage-inducible, alpha
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
KLF13 Kruppel-like factor 13
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PTCRA pre T-cell antigen receptor alpha
RAG2 recombination activating gene 2
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RUVBL2 RuvB-like AAA ATPase 2
STK4 serine/threonine kinase 4
SYK spleen tyrosine kinase
TBATA thymus, brain and testes associated
TET2 tet methylcytosine dioxygenase 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
VAV1 vav 1 guanine nucleotide exchange factor
ZEB1 zinc finger E-box binding homeobox 1
Funding