increased thyroid tumor incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of neoplams in the thyroid occurring in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0010316)
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9 gene mutations causing the increased thyroid tumor incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
MEN1 multiple endocrine neoplasia I
NBN nibrin
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRLR prolactin receptor
PTEN phosphatase and tensin homolog
RB1 retinoblastoma 1
RET ret proto-oncogene
SPTBN1 spectrin, beta, non-erythrocytic 1
THRB thyroid hormone receptor, beta