increased transitional stage t1 b cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater number of a type of transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen; this cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative (Mammalian Phenotype Ontology, MP_0009922)
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4 gene mutations causing the increased transitional stage t1 b cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
CD79A CD79a molecule, immunoglobulin-associated alpha
EPS15 epidermal growth factor receptor pathway substrate 15
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)