increased vasoconstriction Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater ability to constrict the nonstriated, involuntary muscle tissue of the blood vessels (Mammalian Phenotype Ontology, MP_0003025)
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18 gene mutations causing the increased vasoconstriction phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGTR2 angiotensin II receptor, type 2
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
COL3A1 collagen, type III, alpha 1
DDAH1 dimethylarginine dimethylaminohydrolase 1
ESR2 estrogen receptor 2 (ER beta)
HPRT1 hypoxanthine phosphoribosyltransferase 1
IL10 interleukin 10
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
LEPR leptin receptor
NOS3 nitric oxide synthase 3 (endothelial cell)
PDC phosducin
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RGS2 regulator of G-protein signaling 2
TRPC6 transient receptor potential cation channel, subfamily C, member 6