indapamide-2322 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the indapamide-2322 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADORA1 adenosine A1 receptor
ADRA1D adrenoceptor alpha 1D
ASPH aspartate beta-hydroxylase
ASTN1 astrotactin 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BCL2 B-cell CLL/lymphoma 2
C17ORF59 chromosome 17 open reading frame 59
C19ORF66 chromosome 19 open reading frame 66
C1ORF95 chromosome 1 open reading frame 95
C2ORF27A chromosome 2 open reading frame 27A
CAV2 caveolin 2
CD84 CD84 molecule
CD8A CD8a molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CNR2 cannabinoid receptor 2 (macrophage)
COL17A1 collagen, type XVII, alpha 1
COL4A6 collagen, type IV, alpha 6
CPQ carboxypeptidase Q
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYTH4 cytohesin 4
DBP D site of albumin promoter (albumin D-box) binding protein
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DSC2 desmocollin 2
EML2 echinoderm microtubule associated protein like 2
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERP44 endoplasmic reticulum protein 44
ESR1 estrogen receptor 1
F13A1 coagulation factor XIII, A1 polypeptide
FGFR1 fibroblast growth factor receptor 1
FRMD1 FERM domain containing 1
GJD2 gap junction protein, delta 2, 36kDa
GK3P glycerol kinase 3 pseudogene
GLB1L galactosidase, beta 1-like
GYG2 glycogenin 2
HMGN5 high mobility group nucleosome binding domain 5
HSF2BP heat shock transcription factor 2 binding protein
HUS1 HUS1 checkpoint homolog (S. pombe)
IL1R2 interleukin 1 receptor, type II
INO80D INO80 complex subunit D
KERA keratocan
KIAA1462 KIAA1462
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KRT83 keratin 83, type II
LAT2 linker for activation of T cells family, member 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MAPK8 mitogen-activated protein kinase 8
MOGAT2 monoacylglycerol O-acyltransferase 2
MST1L macrophage stimulating 1-like
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUP188 nucleoporin 188kDa
ONECUT2 one cut homeobox 2
ORM1 orosomucoid 1
OSBPL7 oxysterol binding protein-like 7
PCNX pecanex homolog (Drosophila)
PDLIM7 PDZ and LIM domain 7 (enigma)
PHF14 PHD finger protein 14
PML promyelocytic leukemia
POFUT1 protein O-fucosyltransferase 1
PON1 paraoxonase 1
POU2F2 POU class 2 homeobox 2
PRKCE protein kinase C, epsilon
PRMT2IP PRMT2 interacting protein
PSG6 pregnancy specific beta-1-glycoprotein 6
PTHLH parathyroid hormone-like hormone
PVT1 Pvt1 oncogene (non-protein coding)
PWAR5 Prader Willi/Angelman region RNA 5
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SAFB scaffold attachment factor B
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLPI secretory leukocyte peptidase inhibitor
SPN sialophorin
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPP1 secreted phosphoprotein 1
SRSF5 serine/arginine-rich splicing factor 5
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TACC1 transforming, acidic coiled-coil containing protein 1
TBC1D2 TBC1 domain family, member 2
TBXA2R thromboxane A2 receptor
TIAM2 T-cell lymphoma invasion and metastasis 2
TMOD1 tropomodulin 1
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
WIPI2 WD repeat domain, phosphoinositide interacting 2
WNT16 wingless-type MMTV integration site family, member 16
ZBTB44 zinc finger and BTB domain containing 44
ZC3H7B zinc finger CCCH-type containing 7B
ZFAND5 zinc finger, AN1-type domain 5
ZFHX4 zinc finger homeobox 4
ZFP36L2 ZFP36 ring finger protein-like 2
ZFYVE9 zinc finger, FYVE domain containing 9

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AMT aminomethyltransferase
APOD apolipoprotein D
ASAP1-IT1 ASAP1 intronic transcript 1
C14ORF93 chromosome 14 open reading frame 93
C19ORF73 chromosome 19 open reading frame 73
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC132 coiled-coil domain containing 132
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN6 chloride channel, voltage-sensitive 6
CTC1 CTS telomere maintenance complex component 1
CTSK cathepsin K
DMTN dematin actin binding protein
DPY19L1P1 DPY19L1 pseudogene 1
EDAR ectodysplasin A receptor
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
F3 coagulation factor III (thromboplastin, tissue factor)
FAM184A family with sequence similarity 184, member A
FKBP5 FK506 binding protein 5
FLJ11710 uncharacterized protein FLJ11710
FLRT3 fibronectin leucine rich transmembrane protein 3
FLT4 fms-related tyrosine kinase 4
FOXI1 forkhead box I1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HDAC11 histone deacetylase 11
HIST1H4A histone cluster 1, H4a
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXC10 homeobox C10
HP1BP3 heterochromatin protein 1, binding protein 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
INPP5K inositol polyphosphate-5-phosphatase K
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KIAA0513 KIAA0513
KLF3 Kruppel-like factor 3 (basic)
LHX1 LIM homeobox 1
LYPD1 LY6/PLAUR domain containing 1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MCOLN3 mucolipin 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MYO19 myosin XIX
NPM3 nucleophosmin/nucleoplasmin 3
NYNRIN NYN domain and retroviral integrase containing
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFML2A olfactomedin-like 2A
PARD6A par-6 family cell polarity regulator alpha
PGR progesterone receptor
PIBF1 progesterone immunomodulatory binding factor 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
PRICKLE3 prickle homolog 3 (Drosophila)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRODH proline dehydrogenase (oxidase) 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3D RAB3D, member RAS oncogene family
RFTN1 raftlin, lipid raft linker 1
ROM1 retinal outer segment membrane protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SKI SKI proto-oncogene
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC44A1 solute carrier family 44 (choline transporter), member 1
SORBS3 sorbin and SH3 domain containing 3
SOX12 SRY (sex determining region Y)-box 12
SP1 Sp1 transcription factor
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCTA T-cell leukemia translocation altered
TMEM19 transmembrane protein 19
TRABD TraB domain containing
TRAPPC2 trafficking protein particle complex 2
TRNAU1AP tRNA selenocysteine 1 associated protein 1
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF134 zinc finger protein 134
ZNF205 zinc finger protein 205
ZNF211 zinc finger protein 211
ZNF394 zinc finger protein 394
ZNF446 zinc finger protein 446
ZNF506 zinc finger protein 506
ZNF767P zinc finger family member 767, pseudogene