indapamide-3859 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the indapamide-3859 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANGPTL2 angiopoietin-like 2
APLP1 amyloid beta (A4) precursor-like protein 1
ARC activity-regulated cytoskeleton-associated protein
ARHGAP35 Rho GTPase activating protein 35
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
C1ORF61 chromosome 1 open reading frame 61
C1QL1 complement component 1, q subcomponent-like 1
CARTPT CART prepropeptide
CASQ2 calsequestrin 2 (cardiac muscle)
CCDC64 coiled-coil domain containing 64
CD34 CD34 molecule
CDO1 cysteine dioxygenase type 1
CEP295 centrosomal protein 295kDa
CLEC3B C-type lectin domain family 3, member B
COL4A2 collagen, type IV, alpha 2
CPM carboxypeptidase M
CPNE7 copine VII
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
DAPK3 death-associated protein kinase 3
DICER1 dicer 1, ribonuclease type III
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
ELOVL5 ELOVL fatty acid elongase 5
ESR1 estrogen receptor 1
EZR ezrin
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FRMD8 FERM domain containing 8
FUS FUS RNA binding protein
GFI1 growth factor independent 1 transcription repressor
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
HAB1 B1 for mucin
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HFE hemochromatosis
HOXB5 homeobox B5
ICOSLG inducible T-cell co-stimulator ligand
IFT27 intraflagellar transport 27
IL2RB interleukin 2 receptor, beta
IL6ST interleukin 6 signal transducer
INSL4 insulin-like 4 (placenta)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0125 KIAA0125
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRC14 leucine rich repeat containing 14
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDRG2 NDRG family member 2
NPFFR1 neuropeptide FF receptor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP188 nucleoporin 188kDa
PER2 period circadian clock 2
PGLYRP4 peptidoglycan recognition protein 4
PGR progesterone receptor
PLK3 polo-like kinase 3
PLXNB3 plexin B3
PRDM10 PR domain containing 10
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBM48 RNA binding motif protein 48
RGS20 regulator of G-protein signaling 20
RNF126P1 ring finger protein 126 pseudogene 1
RNF6 ring finger protein (C3H2C3 type) 6
RPL10 ribosomal protein L10
RPL13P5 ribosomal protein L13 pseudogene 5
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RXRB retinoid X receptor, beta
S100A7 S100 calcium binding protein A7
SCAND2P SCAN domain containing 2 pseudogene
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A4 solute carrier family 16, member 4
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC35E2 solute carrier family 35, member E2
SMG6 SMG6 nonsense mediated mRNA decay factor
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNX13 sorting nexin 13
TMCC2 transmembrane and coiled-coil domain family 2
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRAF3IP3 TRAF3 interacting protein 3
TSC22D2 TSC22 domain family, member 2
TUBBP5 tubulin, beta pseudogene 5
TYMP thymidine phosphorylase
TYRO3 TYRO3 protein tyrosine kinase
UBA6 ubiquitin-like modifier activating enzyme 6
USP20 ubiquitin specific peptidase 20
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF230 zinc finger protein 230

decreased expression

Symbol Name
ACTL8 actin-like 8
AMH anti-Mullerian hormone
ARR3 arrestin 3, retinal (X-arrestin)
BAHCC1 BAH domain and coiled-coil containing 1
C19ORF73 chromosome 19 open reading frame 73
C4BPA complement component 4 binding protein, alpha
C8ORF44 chromosome 8 open reading frame 44
CBX8 chromobox homolog 8
CCDC71 coiled-coil domain containing 71
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CLDN15 claudin 15
CRLF1 cytokine receptor-like factor 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDIT3 DNA-damage-inducible transcript 3
DEAF1 DEAF1 transcription factor
DEFB126 defensin, beta 126
DGAT1 diacylglycerol O-acyltransferase 1
DOC2A double C2-like domains, alpha
DUSP13 dual specificity phosphatase 13
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHB6 EPH receptor B6
EXD3 exonuclease 3'-5' domain containing 3
FAM155A family with sequence similarity 155, member A
FAM184A family with sequence similarity 184, member A
FBXL2 F-box and leucine-rich repeat protein 2
FGF4 fibroblast growth factor 4
FILIP1L filamin A interacting protein 1-like
FLCN folliculin
FLJ22184
FMOD fibromodulin
FRK fyn-related Src family tyrosine kinase
FXYD5 FXYD domain containing ion transport regulator 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
IFNA14 interferon, alpha 14
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
KIAA0319L KIAA0319-like
KIAA1107 KIAA1107
LAMP3 lysosomal-associated membrane protein 3
LARP6 La ribonucleoprotein domain family, member 6
MAPK12 mitogen-activated protein kinase 12
MATK megakaryocyte-associated tyrosine kinase
MED9 mediator complex subunit 9
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTA2 metastasis associated 1 family, member 2
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NDE1 nudE neurodevelopment protein 1
NRGN neurogranin (protein kinase C substrate, RC3)
NSUN6 NOP2/Sun domain family, member 6
OSGIN1 oxidative stress induced growth inhibitor 1
P3H1 prolyl 3-hydroxylase 1
PADI3 peptidyl arginine deiminase, type III
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PMEL premelanosome protein
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRR14L proline rich 14-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD52 RAD52 homolog (S. cerevisiae)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RNF208 ring finger protein 208
SERGEF secretion regulating guanine nucleotide exchange factor
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SHARPIN SHANK-associated RH domain interactor
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SND1-IT1 SND1 intronic transcript 1
SPON2 spondin 2, extracellular matrix protein
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST5 suppression of tumorigenicity 5
STARD3 StAR-related lipid transfer (START) domain containing 3
TBC1D19 TBC1 domain family, member 19
TEP1 telomerase-associated protein 1
TEX40 testis expressed 40
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM242 transmembrane protein 242
TOM1 target of myb1 (chicken)
TRIM21 tripartite motif containing 21
TYRP1 tyrosinase-related protein 1
WFDC2 WAP four-disulfide core domain 2
XYLT1 xylosyltransferase I
ZBED1 zinc finger, BED-type containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H3 zinc finger CCCH-type containing 3
ZNF408 zinc finger protein 408
ZNF778 zinc finger protein 778