indapamide-3970 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the indapamide-3970 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM29 ADAM metallopeptidase domain 29
ADD2 adducin 2 (beta)
ADGRA2 adhesion G protein-coupled receptor A2
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
AFM afamin
AMACR alpha-methylacyl-CoA racemase
ART1 ADP-ribosyltransferase 1
ARTN artemin
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCORL1 BCL6 corepressor-like 1
BIRC3 baculoviral IAP repeat containing 3
BMP1 bone morphogenetic protein 1
C5ORF42 chromosome 5 open reading frame 42
CADM3 cell adhesion molecule 3
CAPN10 calpain 10
CAPN2 calpain 2, (m/II) large subunit
CCKAR cholecystokinin A receptor
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CLCN4 chloride channel, voltage-sensitive 4
CLEC4M C-type lectin domain family 4, member M
CNTLN centlein, centrosomal protein
CPN2 carboxypeptidase N, polypeptide 2
CSHL1 chorionic somatomammotropin hormone-like 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
DPF1 D4, zinc and double PHD fingers family 1
DPP4 dipeptidyl-peptidase 4
EGR4 early growth response 4
ELN elastin
FGF18 fibroblast growth factor 18
FKRP fukutin related protein
FRMD4B FERM domain containing 4B
FSHB follicle stimulating hormone, beta polypeptide
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLP1R glucagon-like peptide 1 receptor
GPR37L1 G protein-coupled receptor 37 like 1
GYG2 glycogenin 2
HEG1 heart development protein with EGF-like domains 1
HLA-DOA major histocompatibility complex, class II, DO alpha
HP haptoglobin
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL1R2 interleukin 1 receptor, type II
IL2RB interleukin 2 receptor, beta
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KHSRP KH-type splicing regulatory protein
KIAA1456 KIAA1456
LAMB4 laminin, beta 4
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC100131510 uncharacterized LOC100131510
LOC440895 two pore channel 3 pseudogene
LTB4R leukotriene B4 receptor
MDFI MyoD family inhibitor
MNMIP1 manchette microtubule inner protein 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NOVA2 neuro-oncological ventral antigen 2
NPR1 natriuretic peptide receptor 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUDCD3 NudC domain containing 3
NUP54 nucleoporin 54kDa
OMD osteomodulin
PCDH12 protocadherin 12
PLCE1 phospholipase C, epsilon 1
PLCH1 phospholipase C, eta 1
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRDM14 PR domain containing 14
RBBP9 retinoblastoma binding protein 9
RBM12B RNA binding motif protein 12B
RHOH ras homolog family member H
RUNX1 runt-related transcription factor 1
S100A7 S100 calcium binding protein A7
SAFB scaffold attachment factor B
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SNCG synuclein, gamma (breast cancer-specific protein 1)
SSTR5 somatostatin receptor 5
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STIM1 stromal interaction molecule 1
SV2A synaptic vesicle glycoprotein 2A
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
T T, brachyury homolog (mouse)
TBC1D2 TBC1 domain family, member 2
TBCD tubulin folding cofactor D
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFEB transcription factor EB
TMOD1 tropomodulin 1
TRIP6 thyroid hormone receptor interactor 6
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VCX2 variable charge, X-linked 2
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF391 zinc finger protein 391
ZNF440 zinc finger protein 440
ZNF646 zinc finger protein 646
ZNF76 zinc finger protein 76
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAMTSL3 ADAMTS-like 3
ADAP2 ArfGAP with dual PH domains 2
ADGRE1 adhesion G protein-coupled receptor E1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BCO1 beta-carotene oxygenase 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF21 chromosome 11 open reading frame 21
C14ORF79 chromosome 14 open reading frame 79
C1ORF159 chromosome 1 open reading frame 159
C8ORF44 chromosome 8 open reading frame 44
CARTPT CART prepropeptide
CCDC134 coiled-coil domain containing 134
CCDC68 coiled-coil domain containing 68
CCDC71 coiled-coil domain containing 71
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEMIP cell migration inducing protein, hyaluronan binding
CGA glycoprotein hormones, alpha polypeptide
CIDEB cell death-inducing DFFA-like effector b
CLCN6 chloride channel, voltage-sensitive 6
CLDN11 claudin 11
CNGB3 cyclic nucleotide gated channel beta 3
CUZD1 CUB and zona pellucida-like domains 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DGKE diacylglycerol kinase, epsilon 64kDa
DLL3 delta-like 3 (Drosophila)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DRD1 dopamine receptor D1
EML4 echinoderm microtubule associated protein like 4
EXD3 exonuclease 3'-5' domain containing 3
FAM155A family with sequence similarity 155, member A
FAM76A family with sequence similarity 76, member A
FBXO31 F-box protein 31
FLJ22184
FOXN2 forkhead box N2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR1 G protein-coupled receptor 1
GPR157 G protein-coupled receptor 157
GPR176 G protein-coupled receptor 176
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRPR gastrin-releasing peptide receptor
HIST1H2AK histone cluster 1, H2ak
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC4 homeobox C4
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFNA17 interferon, alpha 17
IFT54 intraflagellar transport 54
ITGA8 integrin, alpha 8
ITM2C integral membrane protein 2C
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KLHL25 kelch-like family member 25
MOB3B MOB kinase activator 3B
MUC3A mucin 3A, cell surface associated
OVOL1 ovo-like zinc finger 1
PACS1 phosphofurin acidic cluster sorting protein 1
PADI3 peptidyl arginine deiminase, type III
PAX9 paired box 9
PDE8B phosphodiesterase 8B
PLCD1 phospholipase C, delta 1
PLSCR4 phospholipid scramblase 4
PRAMEF11 PRAME family member 11
PRKCE protein kinase C, epsilon
PRKG2 protein kinase, cGMP-dependent, type II
RND1 Rho family GTPase 1
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RUSC2 RUN and SH3 domain containing 2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SIPA1 signal-induced proliferation-associated 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TBC1D19 TBC1 domain family, member 19
TEX40 testis expressed 40
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLR1 toll-like receptor 1
TM4SF5 transmembrane 4 L six family member 5
TMEM242 transmembrane protein 242
TMLHE trimethyllysine hydroxylase, epsilon
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TSC22D4 TSC22 domain family, member 4
VN1R1 vomeronasal 1 receptor 1
ZFP37 ZFP37 zinc finger protein
ZNF343 zinc finger protein 343
ZNF682 zinc finger protein 682
ZNF696 zinc finger protein 696
ZNF770 zinc finger protein 770