| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the indometacin-2377 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ACVR2B | activin A receptor, type IIB |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARRB1 | arrestin, beta 1 |
| ARRB2 | arrestin, beta 2 |
| ATG10 | autophagy related 10 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CAV2 | caveolin 2 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD300C | CD300c molecule |
| CDC25C | cell division cycle 25C |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CEP164 | centrosomal protein 164kDa |
| CEP250 | centrosomal protein 250kDa |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLEC4A | C-type lectin domain family 4, member A |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CRMP1 | collapsin response mediator protein 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DSC3 | desmocollin 3 |
| DTNA | dystrobrevin, alpha |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EXOSC2 | exosome component 2 |
| FN1 | fibronectin 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
| GAS6 | growth arrest-specific 6 |
| GHRH | growth hormone releasing hormone |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GPX2 | glutathione peroxidase 2 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HDAC7 | histone deacetylase 7 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AL | histone cluster 1, H2al |
| HUNK | hormonally up-regulated Neu-associated kinase |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFNW1 | interferon, omega 1 |
| IL22 | interleukin 22 |
| KAZN | kazrin, periplakin interacting protein |
| KDM7A | lysine (K)-specific demethylase 7A |
| LIMD2 | LIM domain containing 2 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MBP | myelin basic protein |
| MCAM | melanoma cell adhesion molecule |
| MICALL1 | MICAL-like 1 |
| MTSS1 | metastasis suppressor 1 |
| MYO9B | myosin IXB |
| MYOM1 | myomesin 1 |
| NCOA3 | nuclear receptor coactivator 3 |
| NEBL | nebulette |
| NOV | nephroblastoma overexpressed |
| NPPA | natriuretic peptide A |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
| PHF7 | PHD finger protein 7 |
| PLAC4 | placenta-specific 4 |
| PML | promyelocytic leukemia |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| RAD51B | RAD51 paralog B |
| RASAL2 | RAS protein activator like 2 |
| RUNX1 | runt-related transcription factor 1 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STAC | SH3 and cysteine rich domain |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TEX40 | testis expressed 40 |
| TRIM62 | tripartite motif containing 62 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| UBOX5 | U-box domain containing 5 |
| UPB1 | ureidopropionase, beta |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF3 | zinc finger protein 3 |
| ZNF345 | zinc finger protein 345 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AGO4 | argonaute RISC catalytic component 4 |
| ANKRD55 | ankyrin repeat domain 55 |
| ARHGAP25 | Rho GTPase activating protein 25 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BBS1 | Bardet-Biedl syndrome 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CAPRIN2 | caprin family member 2 |
| CCDC15 | coiled-coil domain containing 15 |
| CCDC85C | coiled-coil domain containing 85C |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD82 | CD82 molecule |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CKB | creatine kinase, brain |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EMILIN2 | elastin microfibril interfacer 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM222B | family with sequence similarity 222, member B |
| FBRS | fibrosin |
| FHL3 | four and a half LIM domains 3 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GLTP | glycolipid transfer protein |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPATCH3 | G patch domain containing 3 |
| GRAMD1B | GRAM domain containing 1B |
| HARS2 | histidyl-tRNA synthetase 2, mitochondrial |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IL10RA | interleukin 10 receptor, alpha |
| IL2RG | interleukin 2 receptor, gamma |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MMP9 | matrix metallopeptidase 9 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| NBEAL2 | neurobeachin-like 2 |
| NCS1 | neuronal calcium sensor 1 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PADI1 | peptidyl arginine deiminase, type I |
| PDZD7 | PDZ domain containing 7 |
| PRR4 | proline rich 4 (lacrimal) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB8B | RAB8B, member RAS oncogene family |
| SCAMP4 | secretory carrier membrane protein 4 |
| SEC31B | SEC31 homolog B (S. cerevisiae) |
| SEPW1 | selenoprotein W, 1 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STX17 | syntaxin 17 |
| TCTN2 | tectonic family member 2 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMEM14A | transmembrane protein 14A |
| TRAC | T cell receptor alpha constant |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUBA3C | tubulin, alpha 3c |
| USP6 | ubiquitin specific peptidase 6 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) |
| XAB2 | XPA binding protein 2 |
| YEATS2 | YEATS domain containing 2 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF16 | zinc finger protein 16 |
| ZNF197 | zinc finger protein 197 |
| ZNF222 | zinc finger protein 222 |
| ZNF253 | zinc finger protein 253 |
| ZNF747 | zinc finger protein 747 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| ZW10 | zw10 kinetochore protein |