| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the indometacin-452 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AK2 | adenylate kinase 2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANGPTL4 | angiopoietin-like 4 |
| ARMC7 | armadillo repeat containing 7 |
| ATG13 | autophagy related 13 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BMP7 | bone morphogenetic protein 7 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CBX6 | chromobox homolog 6 |
| CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 |
| CD58 | CD58 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIITA | class II, major histocompatibility complex, transactivator |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CROT | carnitine O-octanoyltransferase |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DPP4 | dipeptidyl-peptidase 4 |
| EGFR | epidermal growth factor receptor |
| EMC1 | ER membrane protein complex subunit 1 |
| EMC9 | ER membrane protein complex subunit 9 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FAM222B | family with sequence similarity 222, member B |
| FAM89B | family with sequence similarity 89, member B |
| FKBP1A | FK506 binding protein 1A, 12kDa |
| FKBPL | FK506 binding protein like |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| HBEGF | heparin-binding EGF-like growth factor |
| HIRIP3 | HIRA interacting protein 3 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFRD1 | interferon-related developmental regulator 1 |
| ITGB5 | integrin, beta 5 |
| JMJD4 | jumonji domain containing 4 |
| JUN | jun proto-oncogene |
| KTN1 | kinectin 1 (kinesin receptor) |
| LPIN1 | lipin 1 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LUZP1 | leucine zipper protein 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MYL10 | myosin, light chain 10, regulatory |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NDRG2 | NDRG family member 2 |
| OTUD4 | OTU deubiquitinase 4 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PADI1 | peptidyl arginine deiminase, type I |
| PISD | phosphatidylserine decarboxylase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLIN2 | perilipin 2 |
| PML | promyelocytic leukemia |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PPP4C | protein phosphatase 4, catalytic subunit |
| PRKX | protein kinase, X-linked |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RARG | retinoic acid receptor, gamma |
| RBM10 | RNA binding motif protein 10 |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RITA1 | RBPJ interacting and tubulin associated 1 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS2 | ribosomal protein S2 |
| RUNX1 | runt-related transcription factor 1 |
| SFN | stratifin |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| SSPN | sarcospan |
| STAG1 | stromal antigen 1 |
| TADA3 | transcriptional adaptor 3 |
| TMC6 | transmembrane channel-like 6 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TOB2 | transducer of ERBB2, 2 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN32 | tetraspanin 32 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| USP20 | ubiquitin specific peptidase 20 |
| WDR46 | WD repeat domain 46 |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF768 | zinc finger protein 768 |
| Symbol | Name |
|---|---|
| ADRA2B | adrenoceptor alpha 2B |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| APOD | apolipoprotein D |
| ART3 | ADP-ribosyltransferase 3 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| CA6 | carbonic anhydrase VI |
| CA9 | carbonic anhydrase IX |
| CD2 | CD2 molecule |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CHGB | chromogranin B |
| CHRM4 | cholinergic receptor, muscarinic 4 |
| CHRM5 | cholinergic receptor, muscarinic 5 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| COL5A2 | collagen, type V, alpha 2 |
| COLEC12 | collectin sub-family member 12 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTGF | connective tissue growth factor |
| CYP2C19 | cytochrome P450, family 2, subfamily C, polypeptide 19 |
| DAGLA | diacylglycerol lipase, alpha |
| DENND6B | DENN/MADD domain containing 6B |
| DNASE1L2 | deoxyribonuclease I-like 2 |
| ETV7 | ets variant 7 |
| FAM46C | family with sequence similarity 46, member C |
| FCGR1B | Fc fragment of IgG, high affinity Ib, receptor (CD64) |
| FZD8 | frizzled class receptor 8 |
| GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GDF3 | growth differentiation factor 3 |
| GPR27 | G protein-coupled receptor 27 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| IFNA17 | interferon, alpha 17 |
| IGFLR1 | IGF-like family receptor 1 |
| IL10RA | interleukin 10 receptor, alpha |
| IL22RA1 | interleukin 22 receptor, alpha 1 |
| INHBC | inhibin, beta C |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KCNE1 | potassium channel, voltage gated subfamily E regulatory beta subunit 1 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLHL25 | kelch-like family member 25 |
| KRT85 | keratin 85, type II |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LMTK2 | lemur tyrosine kinase 2 |
| LOC440792 | proline dehydrogenase (oxidase) 1 pseudogene |
| LOC441601 | septin 7 pseudogene |
| LYRM9 | LYR motif containing 9 |
| MAGEC1 | melanoma antigen family C1 |
| MANSC1 | MANSC domain containing 1 |
| MC5R | melanocortin 5 receptor |
| MPPED1 | metallophosphoesterase domain containing 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MYNN | myoneurin |
| N4BP3 | NEDD4 binding protein 3 |
| NCF2 | neutrophil cytosolic factor 2 |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NELL2 | NEL-like 2 (chicken) |
| NLK | nemo-like kinase |
| NPTX1 | neuronal pentraxin I |
| NTNG1 | netrin G1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NXPH3 | neurexophilin 3 |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PALM | paralemmin |
| PENK | proenkephalin |
| PLAC1 | placenta-specific 1 |
| PLK2 | polo-like kinase 2 |
| PNOC | prepronociceptin |
| PPP1R17 | protein phosphatase 1, regulatory subunit 17 |
| PRKCE | protein kinase C, epsilon |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| RASL10A | RAS-like, family 10, member A |
| RBM4B | RNA binding motif protein 4B |
| RLBP1 | retinaldehyde binding protein 1 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SETDB1 | SET domain, bifurcated 1 |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SPP2 | secreted phosphoprotein 2, 24kDa |
| STX5 | syntaxin 5 |
| TAS2R14 | taste receptor, type 2, member 14 |
| THBS2 | thrombospondin 2 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TMPRSS5 | transmembrane protease, serine 5 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 |
| TRIM45 | tripartite motif containing 45 |
| TRIM66 | tripartite motif containing 66 |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| WDR62 | WD repeat domain 62 |
| ZBED2 | zinc finger, BED-type containing 2 |
