infertility Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility. (Experimental Factor Ontology, EFO_0000545)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0000789
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Genes

37 genes associated with the infertility phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AMH anti-Mullerian hormone
AMHR2 anti-Mullerian hormone receptor, type II
AR androgen receptor
AURKC aurora kinase C
C21ORF59 chromosome 21 open reading frame 59
CATSPER1 cation channel, sperm associated 1
CCDC39 coiled-coil domain containing 39
CCDC40 coiled-coil domain containing 40
CCNO cyclin O
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CTNS cystinosin, lysosomal cystine transporter
DNAAF1 dynein, axonemal, assembly factor 1
DNAAF3 dynein, axonemal, assembly factor 3
DNAAF5 dynein, axonemal, assembly factor 5
DNAI1 dynein, axonemal, intermediate chain 1
DNAI2 dynein, axonemal, intermediate chain 2
DYX1C1 dyslexia susceptibility 1 candidate 1
FOXL2 forkhead box L2
GBA2 glucosidase, beta (bile acid) 2
GOPC golgi-associated PDZ and coiled-coil motif containing
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
KLHL10 kelch-like family member 10
LHB luteinizing hormone beta polypeptide
NANOS1 nanos homolog 1 (Drosophila)
NDN necdin, melanoma antigen (MAGE) family member
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PGR progesterone receptor
PRLR prolactin receptor
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RNF216 ring finger protein 216
RSPH1 radial spoke head 1 homolog (Chlamydomonas)
SEPT12 septin 12
SNRPN small nuclear ribonucleoprotein polypeptide N
SPATA16 spermatogenesis associated 16
ZMYND10 zinc finger, MYND-type containing 10
ZP1 zona pellucida glycoprotein 1 (sperm receptor)