inflammatory bowel disease Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An intestinal disease characterized by inflammation located_in all parts of digestive tract. (Human Disease Ontology, DOID_0050589)
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Genes

78 genes associated with the disease inflammatory bowel disease in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AOX1 aldehyde oxidase 1
APC adenomatous polyposis coli
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BSN bassoon presynaptic cytomatrix protein
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CLEC7A C-type lectin domain family 7, member A
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCC DCC netrin 1 receptor
DEFA5 defensin, alpha 5, Paneth cell-specific
DLG5 discs, large homolog 5 (Drosophila)
F2 coagulation factor II (thrombin)
FAAH fatty acid amide hydrolase
FLG filaggrin
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
IBD5 inflammatory bowel disease 5
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL10 interleukin 10
IL17F interleukin 17F
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL23R interleukin 23 receptor
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL4R interleukin 4 receptor
IL5 interleukin 5
IRGM immunity-related GTPase family, M
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB7 integrin, beta 7
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
KRAS Kirsten rat sarcoma viral oncogene homolog
LMAN1 lectin, mannose-binding, 1
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MEFV Mediterranean fever
MEP1A meprin A, alpha (PABA peptide hydrolase)
MLH1 mutL homolog 1
MOCOS molybdenum cofactor sulfurase
MST1 macrophage stimulating 1
MST1R macrophage stimulating 1 receptor
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPSR1 neuropeptide S receptor 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
OCTN3 organic cation transporter 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PPARG peroxisome proliferator-activated receptor gamma
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REEP6 receptor accessory protein 6
SELE selectin E
SELL selectin L
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
TF transferrin
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53 tumor protein p53
TPMT thiopurine S-methyltransferase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XDH xanthine dehydrogenase