influenza Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system. (Experimental Factor Ontology, EFO_0001669)
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Genes

207 genes co-occuring with the biological term influenza in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE2 angiotensin I converting enzyme 2
ACTN4 actinin, alpha 4
ADAR adenosine deaminase, RNA-specific
AGFG1 ArfGAP with FG repeats 1
AICDA activation-induced cytidine deaminase
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ANXA2 annexin A2
ANXA6 annexin A6
APCS amyloid P component, serum
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARHGAP21 Rho GTPase activating protein 21
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATXN10 ataxin 10
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL2L2 BCL2-like 2
BST2 bone marrow stromal cell antigen 2
C14ORF166 chromosome 14 open reading frame 166
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCNT1 cyclin T1
CD209 CD209 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD4 CD4 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD81 CD81 molecule
CD8A CD8a molecule
CDC42 cell division cycle 42
CDK9 cyclin-dependent kinase 9
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD6 chromodomain helicase DNA binding protein 6
CHRM2 cholinergic receptor, muscarinic 2
CLEC4M C-type lectin domain family 4, member M
CLU clusterin
COX6C cytochrome c oxidase subunit VIc
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFA1 defensin, alpha 1
DEFB103B defensin, beta 103B
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DLG1 discs, large homolog 1 (Drosophila)
DMBT1 deleted in malignant brain tumors 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EBI3 Epstein-Barr virus induced 3
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF4B eukaryotic translation initiation factor 4B
EIF4E eukaryotic translation initiation factor 4E
ERN1 endoplasmic reticulum to nucleus signaling 1
ERVW-1 endogenous retrovirus group W, member 1
F2 coagulation factor II (thrombin)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FHL2 four and a half LIM domains 2
FN1 fibronectin 1
GAS8 growth arrest-specific 8
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
HAVCR2 hepatitis A virus cellular receptor 2
HAX1 HCLS1 associated protein X-1
HDAC6 histone deacetylase 6
HDAC8 histone deacetylase 8
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
HSPA8 heat shock 70kDa protein 8
IFIH1 interferon induced with helicase C domain 1
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IFNA1 interferon, alpha 1
IFNA2 interferon, alpha 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL15 interleukin 15
IL27 interleukin 27
IL32 interleukin 32
IL6 interleukin 6
ILF3 interleukin enhancer binding factor 3, 90kDa
IPO5 importin 5
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
ITK IL2-inducible T-cell kinase
IVNS1ABP influenza virus NS1A binding protein
JUN jun proto-oncogene
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DL5B killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLK12 kallikrein-related peptidase 12
KLK5 kallikrein-related peptidase 5
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNA4 karyopherin alpha 4 (importin alpha 3)
LAMP3 lysosomal-associated membrane protein 3
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS8 lectin, galactoside-binding, soluble, 8
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MAVS mitochondrial antiviral signaling protein
MBL2 mannose-binding lectin (protein C) 2, soluble
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR141 microRNA 141
MIR146A microRNA 146a
MIR29A microRNA 29a
MIR29C microRNA 29c
MIR4276 microRNA 4276
MIR939 microRNA 939
MIRLET7C microRNA let-7c
MOAP1 modulator of apoptosis 1
MUC1 mucin 1, cell surface associated
MX1 MX dynamin-like GTPase 1
MYL1 myosin, light chain 1, alkali; skeletal, fast
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCR1 natural cytotoxicity triggering receptor 1
NOS2 nitric oxide synthase 2, inducible
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUCLEOLIN nucleolin multifunctional protein
NXF1 nuclear RNA export factor 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP10 poly (ADP-ribose) polymerase family, member 10
PDCD1 programmed cell death 1
PEPD peptidase D
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD2 phospholipase D2
PLG plasminogen
PML promyelocytic leukemia
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP6C protein phosphatase 6, catalytic subunit
PRKD3 protein kinase D3
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTX3 pentraxin 3, long
RAB11A RAB11A, member RAS oncogene family
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RSAD2 radical S-adenosyl methionine domain containing 2
RUVBL2 RuvB-like AAA ATPase 2
SCRIB scribbled planar cell polarity protein
SETD7 SET domain containing (lysine methyltransferase) 7
SFPQ splicing factor proline/glutamine-rich
SFTPB surfactant protein B
SFTPD surfactant protein D
SGK1 serum/glucocorticoid regulated kinase 1
SGPL1 sphingosine-1-phosphate lyase 1
SIVA1 SIVA1, apoptosis-inducing factor
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SPHK1 sphingosine kinase 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STAT1 signal transducer and activator of transcription 1, 91kDa
STAU1 staufen double-stranded RNA binding protein 1
SUMO1 small ubiquitin-like modifier 1
TGFB1 transforming growth factor, beta 1
TLR10 toll-like receptor 10
TLR3 toll-like receptor 3
TMPRSS11D transmembrane protease, serine 11D
TMPRSS11E transmembrane protease, serine 11E
TMPRSS13 transmembrane protease, serine 13
TMPRSS2 transmembrane protease, serine 2
TMPRSS4 transmembrane protease, serine 4
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TP53 tumor protein p53
TRAF1 TNF receptor-associated factor 1
TRIM22 tripartite motif containing 22
TSG101 tumor susceptibility 101
TXN thioredoxin
UBE2I ubiquitin-conjugating enzyme E2I
VEGFA vascular endothelial growth factor A
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)