inhibitors Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

853 genes co-occuring with the biological term inhibitors in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACAN aggrecan
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
ACKR3 atypical chemokine receptor 3
ACVR1 activin A receptor, type I
ACVR2B activin A receptor, type IIB
ADAM15 ADAM metallopeptidase domain 15
ADAM17 ADAM metallopeptidase domain 17
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADD1 adducin 1 (alpha)
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB1 adrenoceptor beta 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AHSG alpha-2-HS-glycoprotein
AKAP13 A kinase (PRKA) anchor protein 13
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALCAM activated leukocyte cell adhesion molecule
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX12 arachidonate 12-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALPI alkaline phosphatase, intestinal
ALPL alkaline phosphatase, liver/bone/kidney
AMACR alpha-methylacyl-CoA racemase
AMY2A amylase, alpha 2A (pancreatic)
ANGPT2 angiopoietin 2
ANO1 anoctamin 1, calcium activated chloride channel
ANPEP alanyl (membrane) aminopeptidase
ANXA6 annexin A6
APAF1 apoptotic peptidase activating factor 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APLP2 amyloid beta (A4) precursor-like protein 2
APOB apolipoprotein B
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AQP9 aquaporin 9
AR androgen receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
AREG amphiregulin
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASIC3 acid sensing (proton gated) ion channel 3
ATAD2 ATPase family, AAA domain containing 2
ATF1 activating transcription factor 1
ATM ATM serine/threonine kinase
ATOH1 atonal homolog 1 (Drosophila)
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATR ATR serine/threonine kinase
ATRIP ATR interacting protein
AURKA aurora kinase A
AURKB aurora kinase B
AXIN1 axin 1
AXL AXL receptor tyrosine kinase
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BACE1 beta-site APP-cleaving enzyme 1
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BGN biglycan
BID BH3 interacting domain death agonist
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BMF Bcl2 modifying factor
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP2 bone morphogenetic protein 2
BMP7 bone morphogenetic protein 7
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD2 bromodomain containing 2
BRD4 bromodomain containing 4
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
C4BPA complement component 4 binding protein, alpha
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CA4 carbonic anhydrase IV
CA9 carbonic anhydrase IX
CAPN3 calpain 3, (p94)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CC2D1A coiled-coil and C2 domain containing 1A
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCKBR cholecystokinin B receptor
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND1 cyclin D1
CCNE1 cyclin E1
CCNT1 cyclin T1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD1D CD1d molecule
CD24 CD24 molecule
CD274 CD274 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD4 CD4 molecule
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD6 CD6 molecule
CD7 CD7 molecule
CD70 CD70 molecule
CD80 CD80 molecule
CDC20 cell division cycle 20
CDC25C cell division cycle 25C
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDK12 cyclin-dependent kinase 12
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK6 cyclin-dependent kinase 6
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEL carboxyl ester lipase
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CFI complement factor I
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAT choline O-acetyltransferase
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHGA chromogranin A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHKA choline kinase alpha
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHTOP chromatin target of PRMT1
CHUK conserved helix-loop-helix ubiquitous kinase
CLDN2 claudin 2
CMA1 chymase 1, mast cell
COL1A1 collagen, type I, alpha 1
COL4A2 collagen, type IV, alpha 2
COMT catechol-O-methyltransferase
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREB1 cAMP responsive element binding protein 1
CREB3L1 cAMP responsive element binding protein 3-like 1
CREBBP CREB binding protein
CRP C-reactive protein, pentraxin-related
CRTC2 CREB regulated transcription coactivator 2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSN2 casein beta
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CST7 cystatin F (leukocystatin)
CTAG1B cancer/testis antigen 1B
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTSC cathepsin C
CTSD cathepsin D
CTSK cathepsin K
CTTN cortactin
CUL5 cullin 5
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP3A cytochrome P450, family 3, subfamily A
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAO D-amino-acid oxidase
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDR2 discoidin domain receptor tyrosine kinase 2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DEC1 deleted in esophageal cancer 1
DEFA1 defensin, alpha 1
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DGAT1 diacylglycerol O-acyltransferase 1
DHODH dihydroorotate dehydrogenase (quinone)
DIABLO diablo, IAP-binding mitochondrial protein
DICER1 dicer 1, ribonuclease type III
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLL1 delta-like 1 (Drosophila)
DNM1 dynamin 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPP3 dipeptidyl-peptidase 3
DPP4 dipeptidyl-peptidase 4
DPYD dihydropyrimidine dehydrogenase
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP6 dual specificity phosphatase 6
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
E2F1 E2F transcription factor 1
EBP emopamil binding protein (sterol isomerase)
EDN1 endothelin 1
EDNRB endothelin receptor type B
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
ELK1 ELK1, member of ETS oncogene family
ENGASE endo-beta-N-acetylglucosaminidase
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHA2 EPH receptor A2
EPHX2 epoxide hydrolase 2, cytoplasmic
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC1 excision repair cross-complementation group 1
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F10 coagulation factor X
F11 coagulation factor XI
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
F9 coagulation factor IX
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FASN fatty acid synthase
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FDPS farnesyl diphosphate synthase
FEN1 flap structure-specific endonuclease 1
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FKBP5 FK506 binding protein 5
FLG filaggrin
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FLT4 fms-related tyrosine kinase 4
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXD3 forkhead box D3
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FRK fyn-related Src family tyrosine kinase
FRZB frizzled-related protein
FSHR follicle stimulating hormone receptor
FUBP1 far upstream element (FUSE) binding protein 1
FURIN furin (paired basic amino acid cleaving enzyme)
FYN FYN proto-oncogene, Src family tyrosine kinase
G6PC2 glucose-6-phosphatase, catalytic, 2
G6PD glucose-6-phosphate dehydrogenase
GADD45A growth arrest and DNA-damage-inducible, alpha
GALK1 galactokinase 1
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GAS6 growth arrest-specific 6
GAST gastrin
GCG glucagon
GCH1 GTP cyclohydrolase 1
GDF15 growth differentiation factor 15
GIPR gastric inhibitory polypeptide receptor
GLI1 GLI family zinc finger 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GOPC golgi-associated PDZ and coiled-coil motif containing
GP6 glycoprotein VI (platelet)
GPER1 G protein-coupled estrogen receptor 1
GPNMB glycoprotein (transmembrane) nmb
GPX3 glutathione peroxidase 3
GRB2 growth factor receptor-bound protein 2
GREM1 gremlin 1, DAN family BMP antagonist
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRPR gastrin-releasing peptide receptor
GSG2 germ cell associated 2 (haspin)
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
H2AFZ H2A histone family, member Z
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HBEGF heparin-binding EGF-like growth factor
HCAR2 hydroxycarboxylic acid receptor 2
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC5 histone deacetylase 5
HDAC6 histone deacetylase 6
HDAC8 histone deacetylase 8
HDAC9 histone deacetylase 9
HDC histidine decarboxylase
HES1 hes family bHLH transcription factor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HINFP histone H4 transcription factor
HINT1 histidine triad nucleotide binding protein 1
HIST4H4 histone cluster 4, H4
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HN1 hematological and neurological expressed 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HRK harakiri, BCL2 interacting protein
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTRA2 HtrA serine peptidase 2
HTT huntingtin
HUS1 HUS1 checkpoint homolog (S. pombe)
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
IFN1@ interferon, type 1, cluster
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL10 interleukin 10
IL12B interleukin 12B
IL15 interleukin 15
IL17A interleukin 17A
IL1B interleukin 1, beta
IL2 interleukin 2
IL23A interleukin 23, alpha subunit p19
IL2RA interleukin 2 receptor, alpha
IL31 interleukin 31
IL33 interleukin 33
IL5 interleukin 5
IL6 interleukin 6
ILK integrin-linked kinase
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
INPPL1 inositol polyphosphate phosphatase-like 1
INS insulin
IRAK4 interleukin-1 receptor-associated kinase 4
ISG15 ISG15 ubiquitin-like modifier
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JUN jun proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNIP3 Kv channel interacting protein 3, calsenilin
KCTD21 potassium channel tetramerization domain containing 21
KCTD6 potassium channel tetramerization domain containing 6
KDM1A lysine (K)-specific demethylase 1A
KDM3A lysine (K)-specific demethylase 3A
KDM5B lysine (K)-specific demethylase 5B
KDR kinase insert domain receptor
KIF11 kinesin family member 11
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF5 Kruppel-like factor 5 (intestinal)
KLF6 Kruppel-like factor 6
KLK13 kallikrein-related peptidase 13
KLK4 kallikrein-related peptidase 4
KLK5 kallikrein-related peptidase 5
KLK7 kallikrein-related peptidase 7
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LDHB lactate dehydrogenase B
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LGALS3 lectin, galactoside-binding, soluble, 3
LIMK2 LIM domain kinase 2
LMNA lamin A/C
LMNB1 lamin B1
LMNB2 lamin B2
LONP1 lon peptidase 1, mitochondrial
LOX lysyl oxidase
LOXL2 lysyl oxidase-like 2
LRP5 low density lipoprotein receptor-related protein 5
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRRK2 leucine-rich repeat kinase 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LTF lactotransferrin
MALT1 MALT1 paracaspase
MAN2B1 mannosidase, alpha, class 2B, member 1
MAN2B2 mannosidase, alpha, class 2B, member 2
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MASP2 mannan-binding lectin serine peptidase 2
MBD2 methyl-CpG binding domain protein 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MC5R melanocortin 5 receptor
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MECP2 methyl CpG binding protein 2
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR106A microRNA 106a
MIR125B1 microRNA 125b-1
MIR125B2 microRNA 125b-2
MIR143 microRNA 143
MIR145 microRNA 145
MIR17 microRNA 17
MIR181A2 microRNA 181a-2
MIR181B1 microRNA 181b-1
MIR200A microRNA 200a
MIR200B microRNA 200b
MIR200C microRNA 200c
MIR21 microRNA 21
MIR221 microRNA 221
MIR302A microRNA 302a
MIR375 microRNA 375
MITF microphthalmia-associated transcription factor
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPI mannose phosphate isomerase
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSRB3 methionine sulfoxide reductase B3
MT-ND2 MTND2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MVK mevalonate kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYD88 myeloid differentiation primary response 88
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NAMPT nicotinamide phosphoribosyltransferase
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFYA nuclear transcription factor Y, alpha
NFYB nuclear transcription factor Y, beta
NFYC nuclear transcription factor Y, gamma
NGF nerve growth factor (beta polypeptide)
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOTCH4 notch 4
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPAT nuclear protein, ataxia-telangiectasia locus
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
ODC1 ornithine decarboxylase 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OSTF1 osteoclast stimulating factor 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PADI4 peptidyl arginine deiminase, type IV
PAIP1 poly(A) binding protein interacting protein 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PALB2 partner and localizer of BRCA2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARD6A par-6 family cell polarity regulator alpha
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PAWR PRKC, apoptosis, WT1, regulator
PAX5 paired box 5
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD1 programmed cell death 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPK1 3-phosphoinositide dependent protein kinase 1
PEBP1 phosphatidylethanolamine binding protein 1
PELP1 proline, glutamate and leucine rich protein 1
PEPD peptidase D
PHB prohibitin
PHF8 PHD finger protein 8
PI3 peptidase inhibitor 3, skin-derived
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIAS1 protein inhibitor of activated STAT, 1
PIAS3 protein inhibitor of activated STAT, 3
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PISD phosphatidylserine decarboxylase
PLA2G16 phospholipase A2, group XVI
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCG1 phospholipase C, gamma 1
PLG plasminogen
PLIN1 perilipin 1
PLK1 polo-like kinase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PNMT phenylethanolamine N-methyltransferase
POGLUT1 protein O-glucosyltransferase 1
POLG polymerase (DNA directed), gamma
PON1 paraoxonase 1
POU2F1 POU class 2 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPME1 protein phosphatase methylesterase 1
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PPP6C protein phosphatase 6, catalytic subunit
PRAME preferentially expressed antigen in melanoma
PRCP prolylcarboxypeptidase (angiotensinase C)
PREP prolyl endopeptidase
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRL prolactin
PROCR protein C receptor, endothelial
PROS1 protein S (alpha)
PRSS3 protease, serine, 3
PSEN1 presenilin 1
PSEN2 presenilin 2
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTAFR platelet-activating factor receptor
PTEN phosphatase and tensin homolog
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK6 protein tyrosine kinase 6
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
QPCT glutaminyl-peptide cyclotransferase
RAB11A RAB11A, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RBP2 retinol binding protein 2, cellular
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RELN reelin
RET ret proto-oncogene
RHOA ras homolog family member A
RHOB ras homolog family member B
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RLN3 relaxin 3
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPA2 replication protein A2, 32kDa
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RTN4 reticulon 4
RTN4R reticulon 4 receptor
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RXFP3 relaxin/insulin-like family peptide receptor 3
S100A4 S100 calcium binding protein A4
SAMHD1 SAM domain and HD domain 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SDC1 syndecan 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SELPLG selectin P ligand
SENP6 SUMO1/sentrin specific peptidase 6
SEPT9 septin 9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SET SET nuclear proto-oncogene
SETD7 SET domain containing (lysine methyltransferase) 7
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SH2B1 SH2B adaptor protein 1
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLIT1 slit homolog 1 (Drosophila)
SLIT2 slit homolog 2 (Drosophila)
SLPI secretory leukocyte peptidase inhibitor
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMOX spermine oxidase
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SND1 staphylococcal nuclease and tudor domain containing 1
SOST sclerostin
SP1 Sp1 transcription factor
SPHK1 sphingosine kinase 1
SPI1 Spi-1 proto-oncogene
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPP1 secreted phosphoprotein 1
SPRY2 sprouty homolog 2 (Drosophila)
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SRP72 signal recognition particle 72kDa
SRPK1 SRSF protein kinase 1
SRSF6 serine/arginine-rich splicing factor 6
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAG2 stromal antigen 2
STAP2 signal transducing adaptor family member 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
STK4 serine/threonine kinase 4
STMN1 stathmin 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STXBP6 syntaxin binding protein 6 (amisyn)
SULF1 sulfatase 1
SULF2 sulfatase 2
SYK spleen tyrosine kinase
TAC1 tachykinin, precursor 1
TARDBP TAR DNA binding protein
TDP1 tyrosyl-DNA phosphodiesterase 1
TEK TEK tyrosine kinase, endothelial
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TFCP2 transcription factor CP2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
THBD thrombomodulin
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMPRSS15 transmembrane protease, serine 15
TMSB4X thymosin beta 4, X-linked
TMTC1 transmembrane and tetratricopeptide repeat containing 1
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOP1 topoisomerase (DNA) I
TOP1MT topoisomerase (DNA) I, mitochondrial
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP63 tumor protein p63
TPH2 tryptophan hydroxylase 2
TPT1 tumor protein, translationally-controlled 1
TPX2 TPX2, microtubule-associated
TRAF3 TNF receptor-associated factor 3
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPY1 testis specific protein, Y-linked 1
TTK TTK protein kinase
TTR transthyretin
TWIST1 twist family bHLH transcription factor 1
TXN thioredoxin
TYK2 tyrosine kinase 2
TYMP thymidine phosphorylase
TYRO3 TYRO3 protein tyrosine kinase
UBQLN2 ubiquilin 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UMPS uridine monophosphate synthetase
UNG uracil-DNA glycosylase
UROD uroporphyrinogen decarboxylase
UROS uroporphyrinogen III synthase
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WEE1 WEE1 G2 checkpoint kinase
WFDC12 WAP four-disulfide core domain 12
WNT2B wingless-type MMTV integration site family, member 2B
WRN Werner syndrome, RecQ helicase-like
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPA xeroderma pigmentosum, complementation group A
XRCC6P2 X-ray repair complementing defective repair in Chinese hamster cells 6 pseudogene 2
YBX1 Y box binding protein 1
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZNF148 zinc finger protein 148