innate immune response-activating signaling pathway Gene Set

Dataset	GO Biological Process Annotations 2023
Category	structural or functional annotations
Type	biological process
Description	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an innate immune response. (Gene Ontology, GO_0002758)
External Link	http://amigo.geneontology.org/amigo/term/GO_0002758
Similar Terms
Downloads & Tools

Genes

17 genes participating in the innate immune response-activating signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol	Name
AIM2	absent in melanoma 2
CASP1	caspase 1, apoptosis-related cysteine peptidase
CGAS	cyclic GMP-AMP synthase
CLEC4E	C-type lectin domain family 4, member E
HCK	HCK proto-oncogene, Src family tyrosine kinase
INAVA	innate immunity activator
LACC1	laccase (multicopper oxidoreductase) domain containing 1
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
MEFV	Mediterranean fever
NAIP	NLR family, apoptosis inhibitory protein
NLRC4	NLR family, CARD domain containing 4
NLRP1	NLR family, pyrin domain containing 1
NLRP3	NLR family, pyrin domain containing 3
NOD1	nucleotide-binding oligomerization domain containing 1
NOD2	nucleotide-binding oligomerization domain containing 2
PYCARD	PYD and CARD domain containing
STING1	stimulator of interferon response cGAMP interactor 1